Propylene Oxide

Propylene Oxide

SCHEMBL6844507

C=CC(=O)OCC(CC)(COC(=O)C=C)COC(=O)C=C.CC1CO1

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.55
ALDH1A1 P00352 5/20 0.51
TP53 P04637 3/20 0.51
HIF1A Q16665 3/20 0.51
CYP3A4 P08684 2/20 0.51
MAPK1 P28482 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
TSHR P16473 7/20 0.40
HPGD P15428 1/20 0.40
HSD17B10 Q99714 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL238953 0.86 THRB (0.70) THRBALDH1A1TP53HIF1ACYP3A4
SCHEMBL21647280 0.85 THRB (0.54) THRBALDH1A1TP53HIF1ACYP3A4
Oxirane SCHEMBL2295408 0.85 THRB (0.60) THRBALDH1A1TP53HIF1ACYP3A4
Alcohol SCHEMBL7030010 0.83 ALDH1A1 (0.68) THRBALDH1A1TP53HIF1ACYP3A4
SCHEMBL14130577 0.82 ALDH1A1 (0.67) THRBALDH1A1TP53HIF1ACYP3A4
SCHEMBL28543752 0.82 THRB (0.70) THRBALDH1A1TP53HIF1ACYP3A4
Ethylene Glycol SCHEMBL10426882 0.81 ALDH1A1 (0.66) THRBALDH1A1TP53HIF1ACYP3A4
Acrylic Acid SCHEMBL17101615 0.81 THRB (0.64) THRBALDH1A1TP53HIF1ACYP3A4
SCHEMBL39816 0.81 THRB (0.74) THRBALDH1A1TP53HIF1ACYP3A4
Acrylic Acid SCHEMBL18580288 0.81 THRB (0.64) THRBALDH1A1TP53HIF1ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6770421-B2 COMPRISING AN UNSATURATED COMPOUND COMPOSED OF POLYCARBOXYLIC ACID ADDUCT OF BISPHENOL-EPOXY (METH)ACRYLATE, AN ALKYLENE OXIDE-MODIFIED PRODUCT OF (METH)ACRYLATE OR OLIGOMERS THEREOF, AN EPOXY RESIN AND AN INITIATOR OR SENSITIZER NIPPON STEEL CHEMICAL, CO., LTD (JP) 2004-08-03 US disclosed
US-20020103270-A1 Photo- or heat-curable resin composition and multilayer printed wiring board NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2002-08-01 US disclosed