Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 6/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.37 |
| ▸ | CTSA | P10619 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | CCKAR | P32238 | 1/20 | 0.36 |
| ▸ | CCKBR | P32239 | 1/20 | 0.36 |
| ▸ | PLK4 | O00444 | 1/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.35 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8602526 | 0.74 | PTGS2 (0.47) | — | |
| SCHEMBL6844769 | 0.67 | KDM4E (0.46) | LMNASMN1; SMN2SUCNR1PTGDR2KDM4E | |
| SCHEMBL6132023 | 0.67 | MAPK1 (0.67) | SMN1; SMN2KDM4EALDH1A1HPGDMAP4K4 | |
| SCHEMBL2353154 | 0.65 | APEX1 (0.44) | LMNASMN1; SMN2KDM4E | |
| SCHEMBL9890668 | 0.65 | LMNA (0.51) | LMNASMN1; SMN2SUCNR1PTGDR2CYP2C9 | |
| SCHEMBL9890650 | 0.65 | LMNA (0.51) | LMNASMN1; SMN2SUCNR1PTGDR2CYP2C9 | |
| SCHEMBL20279270 | 0.64 | KDM4E (0.44) | DHODHSUCNR1KDM4ECYP2C9MAPK14 | |
| SCHEMBL1807796 | 0.64 | PLK4 (0.40) | LMNASMN1; SMN2DHODHALDH1A1CYP2C9 | |
| SCHEMBL3540535 | 0.64 | SUCNR1 (0.56) | SUCNR1PTGDR2KDM4ECYP2C9CYP2C19 | |
| SCHEMBL1177292 | 0.64 | TSHR (0.63) | LMNASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040242597-A1 | Combination | NYCOMED GMBH (DE) | 2004-12-02 | — | — | US | disclosed |