Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 1/20 | 0.57 |
| ▸ | CDC25B | P30305 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TDP2 | O95551 | 2/20 | 0.40 |
| ▸ | NSD2 | O96028 | 2/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.40 |
| ▸ | PADI1 | Q9ULC6 | 2/20 | 0.40 |
| ▸ | PADI3 | Q9ULW8 | 2/20 | 0.40 |
| ▸ | PADI4 | Q9UM07 | 2/20 | 0.40 |
| ▸ | PADI2 | Q9Y2J8 | 2/20 | 0.40 |
| ▸ | HKDC1 | Q2TB90 | 2/20 | 0.40 |
| ▸ | S100A4 | P26447 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | TERT | O14746 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6846906 | 0.90 | TOP2A (0.72) | TOP2ACDC25BMEN1KMT2ATHRB | |
| SCHEMBL6845596 | 0.86 | TOP2A (0.56) | TOP2ACDC25BMEN1KMT2ATHRB | |
| SCHEMBL7635167 | 0.84 | TOP2A (0.80) | TOP2ACDC25BMEN1KMT2ATHRB | |
| SCHEMBL31237393 | 0.81 | TOP2A (0.70) | TOP2ACDC25BMEN1KMT2ATHRB | |
| SCHEMBL20259222 | 0.81 | TOP2A (0.70) | TOP2ACDC25BMEN1KMT2ATHRB | |
| SCHEMBL7186247 | 0.79 | TOP2A (0.75) | TOP2ACDC25BMEN1KMT2ATHRB | |
| SCHEMBL20259137 | 0.77 | TOP2A (0.51) | TOP2ACDC25BMEN1KMT2ATERT | |
| SCHEMBL6846666 | 0.76 | TOP2A (0.70) | TOP2AMEN1KMT2ATHRBBLM | |
| SCHEMBL6845707 | 0.76 | TOP2A (0.70) | TOP2ACDC25BMEN1KMT2ATHRB | |
| SCHEMBL6845597 | 0.76 | TOP2A (0.70) | TOP2ACDC25BMEN1KMT2ATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1202992-B1 | ASCIDIDEMIN DERIVATIVES AND THEIR THERAPEUTIC APPLICATIONS | CEPHALON FRANCE (FR) | 2004-09-15 | — | — | EP | claimed |
| EP-3548486-B1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2021-10-27 | — | — | EP | disclosed |
| WO-2018104194-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2018-06-14 | — | — | WO | disclosed |