Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PADI1 | Q9ULC6 | 2/20 | 0.40 |
| ▸ | PADI3 | Q9ULW8 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6845707 | 0.90 | TOP2A (0.70) | TOP2AMEN1THRBBLMKMT2A | |
| SCHEMBL6845499 | 0.86 | TOP2A (0.57) | TOP2AMEN1THRBBLMKMT2A | |
| SCHEMBL7635167 | 0.83 | TOP2A (0.80) | TOP2AMEN1THRBBLMKMT2A | |
| SCHEMBL7186247 | 0.78 | TOP2A (0.75) | TOP2AMEN1THRBBLMKMT2A | |
| SCHEMBL6846906 | 0.76 | TOP2A (0.72) | TOP2AMEN1THRBBLMKMT2A | |
| SCHEMBL16072069 | 0.76 | TOP2A (0.51) | TOP2AMEN1THRBBLMKMT2A | |
| SCHEMBL6845597 | 0.75 | TOP2A (0.70) | TOP2AMEN1THRBBLMKMT2A | |
| SCHEMBL6846666 | 0.75 | TOP2A (0.70) | TOP2AMEN1THRBBLMKMT2A | |
| SCHEMBL6846896 | 0.72 | TOP2A (0.66) | TOP2AMEN1THRBBLMKMT2A | |
| SCHEMBL20259203 | 0.72 | TOP2A (0.70) | TOP2AMEN1THRBBLMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1202992-B1 | ASCIDIDEMIN DERIVATIVES AND THEIR THERAPEUTIC APPLICATIONS | CEPHALON FRANCE (FR) | 2004-09-15 | — | — | EP | claimed |