Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | KDM1A | O60341 | 2/20 | 0.58 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL684891 | 0.84 | RAB9A (0.60) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL685236 | 0.83 | KMT2A (0.55) | NPC1RAB9ASMN1; SMN2KDM1AMAOA | |
| SCHEMBL684571 | 0.83 | CYP1A2 (0.61) | NPC1RAB9ASMN1; SMN2KDM1AMAOA | |
| SCHEMBL684996 | 0.82 | MAPT (0.60) | NPC1RAB9ASMN1; SMN2KDM1AMAOA | |
| SCHEMBL683831 | 0.81 | KDM4E (0.65) | NPC1SMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL685111 | 0.80 | RAB9A (0.67) | NPC1RAB9ASMN1; SMN2KDM1AMAOA | |
| SCHEMBL13475712 | 0.79 | NPC1 (0.83) | NPC1RAB9ASMN1; SMN2KDM1AMAOA | |
| SCHEMBL25419611 | 0.78 | RAB9A (0.60) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL25419617 | 0.78 | RAB9A (0.60) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL685019 | 0.78 | CYP1A2 (0.66) | NPC1RAB9ASMN1; SMN2KDM1AMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8455394-B2 | Fungicidal compositions including hydrazone derivatives and copper | DOW AGROSCIENCES, LLC (US) | 2013-06-04 | — | — | US | disclosed |
| US-8455394-B2 | Fungicidal compositions including hydrazone derivatives and copper | DOW AGROSCIENCES, LLC (US) | 2013-06-04 | — | — | US | disclosed |
| US-20120021065-A1 | FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | DOW AGROSCIENCES LLC (US) | 2012-01-26 | — | — | US | disclosed |
| US-20120021065-A1 | FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | DOW AGROSCIENCES LLC (US) | 2012-01-26 | — | — | US | disclosed |
| US-20120010075-A1 | SYNERGISTIC FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | DOW AGROSCIENCES LLC (US) | 2012-01-12 | — | — | US | disclosed |
| US-20120010075-A1 | SYNERGISTIC FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | DOW AGROSCIENCES LLC (US) | 2012-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120010075-A1 | SYNERGISTIC FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | SOD1, CYP51A1, SOD3 | NPC1 1690/4885RAB9A 3846/4885SMN1; SMN2 4107/4885 |
| US-20120021065-A1 | FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | SOD1, CYP51A1, CYP4Z1 | NPC1 1052/4885RAB9A 3616/4885SMN1; SMN2 3775/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.