Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 9/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 8/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.42 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.41 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6844540 | 0.93 | CYP19A1 (0.44) | GRM2NR4A2CYP11B2CYP11B1CYP19A1 | |
| SCHEMBL6844445 | 0.85 | CYP2A6 (0.47) | GRM2CYP11B2CYP11B1CYP19A1CYP2A6 | |
| SCHEMBL6846192 | 0.83 | CYP2A6 (0.44) | GRM2CYP11B2CYP11B1CYP19A1CYP17A1 | |
| SCHEMBL6846125 | 0.75 | CYP11B2 (0.59) | GRM2CYP11B2CYP11B1CYP19A1CYP17A1 | |
| SCHEMBL22515743 | 0.73 | CYP11B2 (0.53) | GRM2CYP11B2CYP11B1CYP19A1CYP17A1 | |
| SCHEMBL6846150 | 0.72 | HTR1D (0.55) | GRM2CYP11B2CYP11B1CYP19A1CYP17A1 | |
| SCHEMBL30146986 | 0.71 | CYP2A6 (0.40) | CYP11B2CYP11B1CYP19A1CYP17A1CYP2A6 | |
| SCHEMBL16751046 | 0.71 | CYP2A6 (0.40) | CYP11B2CYP11B1CYP19A1CYP17A1CYP2A6 | |
| SCHEMBL6845959 | 0.71 | CYP11B1 (0.54) | GRM2CYP11B2CYP11B1CYP19A1CYP17A1 | |
| SCHEMBL6657591 | 0.70 | CYP11B2 (0.56) | GRM2CYP11B2CYP11B1CYP19A1CYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040236110-A1 | Substituted 3-pyridyl indoles and indazoles as c17,20 lyase inhibitors | BAYER PHARMACEUTICALS CORPORATION | 2004-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040236110-A1 | Substituted 3-pyridyl indoles and indazoles as c17,20 lyase inhibitors | CYP17A1, IDO1, CYP21A2 | GRM2 4166/4885NR4A2 4146/4885CYP11B2 53/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.