Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | NAMPT | P43490 | 1/20 | 0.53 |
| ▸ | CCR9 | P51686 | 3/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | BRD1 | O95696 | 1/20 | 0.46 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.46 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.46 |
| ▸ | BRPF3 | Q9ULD4 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | UQCRB | P14927 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6845454 | 0.90 | KMT2A (0.51) | ALDH1A1POLBHTTSMN1; SMN2NAMPT | |
| SCHEMBL6840912 | 0.89 | POLB (0.54) | ALDH1A1POLBHTTSMN1; SMN2NAMPT | |
| SCHEMBL6844273 | 0.87 | BRD4 (0.57) | ALDH1A1POLBHTTSMN1; SMN2BRD4 | |
| SCHEMBL6656125 | 0.86 | MEN1 (0.57) | ALDH1A1HTTSMN1; SMN2BRD4BRD1 | |
| SCHEMBL6844284 | 0.86 | BRD1 (0.53) | POLBNAMPTBRD4BRD1BRPF1 | |
| SCHEMBL6847813 | 0.86 | KEAP1 (0.60) | ALDH1A1HTTSMN1; SMN2BRD4BRD1 | |
| SCHEMBL6658847 | 0.84 | BRPF1 (0.60) | BRD4BRD1BRPF1BRD9BRPF3 | |
| SCHEMBL6659457 | 0.84 | KMT2A (0.48) | ALDH1A1POLBHTTNR1I2BRD4 | |
| SCHEMBL6844486 | 0.82 | KMT2A (0.47) | SMN1; SMN2NAMPTCCR9BRD4BRD1 | |
| SCHEMBL6845979 | 0.81 | BRPF1 (0.53) | ALDH1A1POLBNAMPTBRD4BRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040236110-A1 | Substituted 3-pyridyl indoles and indazoles as c17,20 lyase inhibitors | BAYER PHARMACEUTICALS CORPORATION | 2004-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040236110-A1 | Substituted 3-pyridyl indoles and indazoles as c17,20 lyase inhibitors | CYP17A1, IDO1, CYP21A2 | ALDH1A1 126/4885POLB 2154/4885HTT 3953/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.