Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRPF1 | P55201 | 3/20 | 0.53 |
| ▸ | MET | P08581 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.41 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.40 |
| ▸ | BRD4 | O60885 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6653161 | 0.88 | BRPF1 (0.55) | BRPF1METKDM4ECYP1A2CYP3A4 | |
| SCHEMBL6844273 | 0.84 | BRD4 (0.57) | BRPF1TDP1MEN1MAPTKMT2A | |
| SCHEMBL6840912 | 0.84 | POLB (0.54) | BRPF1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL7028408 | 0.83 | ALDH1A1 (0.58) | BRPF1CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL21671905 | 0.83 | MAPT (0.51) | KDM4ECYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL6656125 | 0.82 | MEN1 (0.57) | BRPF1KDM4EMEN1TP53MAPT | |
| SCHEMBL6840525 | 0.82 | NR1I2 (0.49) | BRPF1KMT2ANAMPTCYP17A1 | |
| SCHEMBL6847813 | 0.81 | KEAP1 (0.60) | BRPF1KDM4ETDP1MEN1MAPT | |
| SCHEMBL6846145 | 0.81 | ALDH1A1 (0.60) | BRPF1CYP1A2CYP3A4CYP2C19TDP1 | |
| SCHEMBL6844284 | 0.81 | BRD1 (0.53) | BRPF1MEN1MAPTKMT2ANAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040236110-A1 | Substituted 3-pyridyl indoles and indazoles as c17,20 lyase inhibitors | BAYER PHARMACEUTICALS CORPORATION | 2004-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040236110-A1 | Substituted 3-pyridyl indoles and indazoles as c17,20 lyase inhibitors | CYP17A1, IDO1, CYP21A2 | BRPF1 2930/4885MET 3547/4885KDM4E 970/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.