Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 3/20 | 0.57 |
| ▸ | BRD1 | O95696 | 2/20 | 0.57 |
| ▸ | BRPF1 | P55201 | 2/20 | 0.57 |
| ▸ | BRD9 | Q9H8M2 | 2/20 | 0.57 |
| ▸ | BRPF3 | Q9ULD4 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6840912 | 0.90 | POLB (0.54) | BRD4BRD1BRPF1BRD9BRPF3 | |
| SCHEMBL6656125 | 0.90 | MEN1 (0.57) | BRD4BRD1BRPF1BRD9BRPF3 | |
| SCHEMBL6665282 | 0.88 | LMNA (0.45) | BRD4BRD1BRPF1BRD9BRPF3 | |
| SCHEMBL6847813 | 0.87 | KEAP1 (0.60) | BRD4BRD1BRPF1BRD9BRPF3 | |
| SCHEMBL6846145 | 0.87 | ALDH1A1 (0.60) | BRD4BRD1BRPF1BRD9BRPF3 | |
| SCHEMBL6659457 | 0.87 | KMT2A (0.48) | BRD4BRD1BRPF1BRD9BRPF3 | |
| SCHEMBL6658847 | 0.87 | BRPF1 (0.60) | BRD4BRD1BRPF1BRD9BRPF3 | |
| SCHEMBL6844284 | 0.87 | BRD1 (0.53) | BRD4BRD1BRPF1BRD9BRPF3 | |
| SCHEMBL6845454 | 0.87 | KMT2A (0.51) | BRD4BRD1BRPF1BRD9BRPF3 | |
| SCHEMBL6844486 | 0.86 | KMT2A (0.47) | BRD4BRD1BRPF1BRD9BRPF3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040236110-A1 | Substituted 3-pyridyl indoles and indazoles as c17,20 lyase inhibitors | BAYER PHARMACEUTICALS CORPORATION | 2004-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040236110-A1 | Substituted 3-pyridyl indoles and indazoles as c17,20 lyase inhibitors | CYP17A1, IDO1, CYP21A2 | BRD4 1450/4885BRD1 1341/4885BRPF1 2930/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.