Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.79 |
| ▸ | MEN1 | O00255 | 7/20 | 0.79 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.79 |
| ▸ | HTT | P42858 | 4/20 | 0.79 |
| ▸ | MAPT | P10636 | 3/20 | 0.79 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.72 |
| ▸ | TP53 | P04637 | 1/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.72 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.72 |
| ▸ | HPGD | P15428 | 1/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.72 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.72 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.71 |
| ▸ | KDM1A | O60341 | 3/20 | 0.66 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.65 |
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 3/20 | 0.63 |
| ▸ | NPC1 | O15118 | 2/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1637462 | 1.00 | KMT2A (0.79) | KMT2AMEN1KDM4EHTTMAPT | |
| SCHEMBL1637464 | 1.00 | KMT2A (0.79) | KMT2AMEN1KDM4EHTTMAPT | |
| SCHEMBL685045 | 0.89 | NTRK1 (0.76) | KMT2AMEN1KDM4EHTTMAPT | |
| SCHEMBL684541 | 0.88 | KDM4E (1.00) | KMT2AMEN1KDM4EHTTMAPT | |
| SCHEMBL684517 | 0.88 | KMT2A (0.74) | KMT2AMEN1KDM4EHTTMAPT | |
| SCHEMBL1638302 | 0.88 | MEN1 (0.63) | KMT2AMEN1KDM4EHTTMAPT | |
| SCHEMBL1638299 | 0.88 | MEN1 (0.63) | KMT2AMEN1KDM4EHTTMAPT | |
| SCHEMBL12767391 | 0.88 | MEN1 (0.63) | KMT2AMEN1KDM4EHTTMAPT | |
| SCHEMBL6568468 | 0.86 | KMT2A (0.71) | KMT2AMEN1KDM4EHTTMAPT | |
| SCHEMBL6568466 | 0.86 | KMT2A (0.71) | KMT2AMEN1KDM4EHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8906829-B2 | Synergistic algicidal compositions including hydrazone derivatives and copper | DOW AGROSCIENCES LLC (US) | 2014-12-09 | — | — | US | disclosed |
| US-8906829-B2 | Synergistic algicidal compositions including hydrazone derivatives and copper | DOW AGROSCIENCES LLC (US) | 2014-12-09 | — | — | US | disclosed |
| US-20120046170-A1 | SYNERGISTIC ALGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | DOW AGROSCIENCES LLC (US) | 2012-02-23 | — | — | US | disclosed |
| US-20120046170-A1 | SYNERGISTIC ALGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | DOW AGROSCIENCES LLC (US) | 2012-02-23 | — | — | US | disclosed |
| WO-2012024494-A1 | SYNERGISTIC ALGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | DOW AGROSCIENCES LLC (US) | 2012-02-23 | — | — | WO | disclosed |
| US-20120010075-A1 | SYNERGISTIC FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | DOW AGROSCIENCES LLC (US) | 2012-01-12 | — | — | US | disclosed |
| US-20120010075-A1 | SYNERGISTIC FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | DOW AGROSCIENCES LLC (US) | 2012-01-12 | — | — | US | disclosed |
| US-20110098309-A1 | METHODS OF INHIBITING THE FORMATION OF AMYLOID-BETA DIFFUSABLE LIGANDS USING ACYLHYDRAZIDE COMPOUNDS | ACUMEN PHARMACEUTICALS, INC. (US) | 2011-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120010075-A1 | SYNERGISTIC FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | SOD1, CYP51A1, SOD3 | KMT2A 1362/4885MEN1 536/4885KDM4E 1473/4885 |
| US-20120046170-A1 | SYNERGISTIC ALGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | ALG1, SOD1, DHPS | KMT2A 2866/4885MEN1 3435/4885KDM4E 4139/4885 |
| US-20110098309-A1 | METHODS OF INHIBITING THE FORMATION OF AMYLOID-BETA DIFFUSABLE LIGANDS USING ACYLHYDRAZIDE COMPOUNDS | APP, APBA1, BACE1 | KMT2A 3625/4885MEN1 2974/4885KDM4E 4638/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.