Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 3/20 | 0.76 |
| ▸ | MEN1 | O00255 | 7/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.72 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.72 |
| ▸ | TP53 | P04637 | 1/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.72 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.72 |
| ▸ | HPGD | P15428 | 1/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.72 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.72 |
| ▸ | MAPT | P10636 | 7/20 | 0.64 |
| ▸ | HTT | P42858 | 4/20 | 0.64 |
| ▸ | KDM1A | O60341 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | BLM | P54132 | 2/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL684635 | 0.89 | KMT2A (0.79) | NTRK1MEN1KMT2AKDM4EMAPK1 | |
| SCHEMBL1637462 | 0.89 | KMT2A (0.79) | NTRK1MEN1KMT2AKDM4EMAPK1 | |
| SCHEMBL1637464 | 0.89 | KMT2A (0.79) | NTRK1MEN1KMT2AKDM4EMAPK1 | |
| SCHEMBL1638504 | 0.86 | NTRK1 (1.00) | NTRK1MEN1KMT2AKDM4EMAPK1 | |
| SCHEMBL1638502 | 0.86 | NTRK1 (1.00) | NTRK1MEN1KMT2AKDM4EMAPK1 | |
| SCHEMBL12766909 | 0.86 | NTRK1 (1.00) | NTRK1MEN1KMT2AKDM4EMAPK1 | |
| SCHEMBL12767391 | 0.86 | MEN1 (0.63) | NTRK1MEN1KMT2AKDM4EMAPK1 | |
| SCHEMBL1638302 | 0.86 | MEN1 (0.63) | NTRK1MEN1KMT2AKDM4EMAPK1 | |
| SCHEMBL1638299 | 0.86 | MEN1 (0.63) | NTRK1MEN1KMT2AKDM4EMAPK1 | |
| SCHEMBL684650 | 0.85 | KMT2A (0.57) | NTRK1MEN1KMT2AKDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8715745-B2 | Fungicidal compositions including hydrazone derivatives and copper | DOW AGROSCIENCES, LLC. (US) | 2014-05-06 | — | — | US | disclosed |
| US-8715745-B2 | Fungicidal compositions including hydrazone derivatives and copper | DOW AGROSCIENCES, LLC. (US) | 2014-05-06 | — | — | US | disclosed |
| US-20120010075-A1 | SYNERGISTIC FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | DOW AGROSCIENCES LLC (US) | 2012-01-12 | — | — | US | disclosed |
| US-20120010075-A1 | SYNERGISTIC FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | DOW AGROSCIENCES LLC (US) | 2012-01-12 | — | — | US | disclosed |
| US-20120009274-A1 | FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | DOW AGROSCIENCES LLC (US) | 2012-01-12 | — | — | US | disclosed |
| US-20120009274-A1 | FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | DOW AGROSCIENCES LLC (US) | 2012-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120010075-A1 | SYNERGISTIC FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | SOD1, CYP51A1, SOD3 | NTRK1 4568/4885MEN1 536/4885KMT2A 1362/4885 |
| US-20120009274-A1 | FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | SOD1, CYP51A1, CYP4Z1 | NTRK1 4662/4885MEN1 508/4885KMT2A 1224/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.