Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 2/20 | 0.55 |
| ▸ | CTSK | P43235 | 2/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.43 |
| ▸ | REN | P00797 | 11/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6744511 | 1.00 | CTSS (0.55) | CTSSCTSKHDAC4HDAC1HDAC6 | |
| SCHEMBL6213346 | 1.00 | CTSS (0.55) | CTSSCTSKHDAC4HDAC1HDAC6 | |
| SCHEMBL4324431 | 0.85 | CTSK (0.46) | CTSSCTSKHDAC4HDAC1HDAC6 | |
| SCHEMBL4317181 | 0.85 | CTSK (0.46) | CTSSCTSKHDAC4HDAC1HDAC6 | |
| SCHEMBL4317184 | 0.85 | CTSK (0.46) | CTSSCTSKHDAC4HDAC1HDAC6 | |
| SCHEMBL4314582 | 0.85 | CTSK (0.46) | CTSSCTSKHDAC4HDAC1HDAC6 | |
| SCHEMBL4324433 | 0.85 | CTSK (0.46) | CTSSCTSKHDAC4HDAC1HDAC6 | |
| SCHEMBL4314585 | 0.85 | CTSK (0.46) | CTSSCTSKHDAC4HDAC1HDAC6 | |
| SCHEMBL5096660 | 0.84 | CTSS (0.56) | CTSSCTSKHDAC4HDAC1HDAC6 | |
| SCHEMBL5949181 | 0.79 | CTSK (0.50) | CTSSCTSKHDAC4HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040229863-A1 | Protease inhibitors | SMITHKLINE BEECHAM CORPORATION | 2004-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040229863-A1 | Protease inhibitors | CTSS, CTSE, CTSF | CTSS 1/4885CTSK 6/4885HDAC4 703/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.