Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKD3 | O94806 | 1/20 | 0.54 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.54 |
| ▸ | FRK | P42685 | 1/20 | 0.54 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.54 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.54 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.54 |
| ▸ | GSK3B | P49841 | 1/20 | 0.54 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.54 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.54 |
| ▸ | MAPK13 | O15264 | 15/20 | 0.54 |
| ▸ | MAPK12 | P53778 | 15/20 | 0.54 |
| ▸ | MAPK11 | Q15759 | 15/20 | 0.54 |
| ▸ | MAPK14 | Q16539 | 15/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6844082 | 0.84 | MAPK13 (0.69) | MAPK13MAPK12MAPK11MAPK14PTGS2 | |
| SCHEMBL8419683 | 0.79 | PRKD3 (0.54) | PRKD3MAP4K4FRKMAPK9CSNK1A1 | |
| SCHEMBL5847870 | 0.77 | SIGMAR1 (0.53) | PRKD3MAP4K4FRKMAPK9CSNK1A1 | |
| SCHEMBL6161437 | 0.76 | SIGMAR1 (0.55) | PRKD3MAP4K4FRKMAPK9CSNK1A1 | |
| SCHEMBL6844336 | 0.76 | MAPK14 (0.64) | PRKD3MAP4K4FRKMAPK9CSNK1A1 | |
| SCHEMBL14288452 | 0.76 | MAP4K4 (0.86) | PRKD3MAP4K4FRKMAPK9CSNK1A1 | |
| SCHEMBL10441604 | 0.76 | MAP4K4 (0.63) | PRKD3MAP4K4FRKMAPK9CSNK1A1 | |
| SCHEMBL12545505 | 0.75 | CYP11B1 (0.49) | MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL5093475 | 0.75 | MAP4K4 (0.62) | PRKD3MAP4K4FRKMAPK9CSNK1A1 | |
| SCHEMBL10801666 | 0.75 | PRKD3 (0.62) | PRKD3MAP4K4FRKMAPK9CSNK1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040162328-A1 | Compounds of the family of 3-alkyl-(4,5-diphenyl-imidazol-1-yl) and their use as soothing agents | L'OREAL (FR) | 2004-08-19 | — | — | US | claimed |
| US-20040162328-A1 | Compounds of the family of 3-alkyl-(4,5-diphenyl-imidazol-1-yl) and their use as soothing agents | L'OREAL (FR) | 2004-08-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040162328-A1 | Compounds of the family of 3-alkyl-(4,5-diphenyl-imidazol-1-yl) and their use as soothing agents | TRPV1, TRPA1, TRPV3 | PRKD3 1143/4885MAP4K4 3127/4885FRK 369/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.