Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 3/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.68 |
| ▸ | RECQL | P46063 | 1/20 | 0.68 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25219229 | 0.84 | CYP1A2 (0.83) | CYP2C19CYP1A2RECQLHTTSMN1; SMN2 | |
| SCHEMBL11601049 | 0.83 | CYP1A2 (0.63) | CYP2C19CYP1A2RECQLHTTSMN1; SMN2 | |
| SCHEMBL1457625 | 0.83 | GAA (0.72) | CYP2C19CYP1A2RECQLHTTSMN1; SMN2 | |
| SCHEMBL27600191 | 0.83 | CYP1A2 (0.63) | CYP2C19CYP1A2RECQLHTTSMN1; SMN2 | |
| SCHEMBL1457624 | 0.83 | GAA (0.72) | CYP2C19CYP1A2RECQLHTTSMN1; SMN2 | |
| SCHEMBL25522729 | 0.83 | CYP1A2 (0.71) | CYP2C19CYP1A2RECQLHTTSMN1; SMN2 | |
| SCHEMBL5718940 | 0.81 | USP2 (0.72) | CYP2C19CYP1A2RECQLHTTSMN1; SMN2 | |
| SCHEMBL27582896 | 0.81 | CYP1A2 (1.00) | CYP2C19CYP1A2RECQLHTTSMN1; SMN2 | |
| SCHEMBL15749696 | 0.80 | CYP1A2 (0.63) | CYP2C19CYP1A2RECQLHTTSMN1; SMN2 | |
| SCHEMBL27600244 | 0.80 | RECQL (0.91) | CYP2C19CYP1A2RECQLHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110118464-A1 | HALOGENATED XANTHINE DERIVATIVES AND PRECURSORS THEREOF FOR ANTI-CANCER AND ANTI-METASTASIS ACTIVITY AND PREPARING METHOD THEREOF | KAOHSIUNG MEDICAL UNIVERSITY | 2011-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110118464-A1 | HALOGENATED XANTHINE DERIVATIVES AND PRECURSORS THEREOF FOR ANTI-CANCER AND ANTI-METASTASIS ACTIVITY AND PREPARING METHOD THEREOF | TK1, XDH, KYAT1 | CYP2C19 2772/4885CYP1A2 769/4885RECQL 3896/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.