Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC5 | P28715 | 1/20 | 0.52 |
| ▸ | FEN1 | P39748 | 1/20 | 0.52 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6850540 | 0.91 | P2RX7 (0.50) | ERCC5FEN1ALDH1A1TSHRHDAC6 | |
| SCHEMBL6849923 | 0.86 | P2RX7 (0.50) | ERCC5FEN1HSD11B1ALDH1A1TSHR | |
| SCHEMBL6847838 | 0.86 | ERCC5 (0.53) | ERCC5FEN1HSD11B1ALDH1A1HTT | |
| SCHEMBL6848952 | 0.84 | NPC1 (0.53) | ERCC5FEN1HSD11B1ALDH1A1HTT | |
| SCHEMBL17036968 | 0.84 | P2RX7 (0.47) | ERCC5FEN1ALDH1A1TSHRHDAC6 | |
| SCHEMBL12098938 | 0.83 | ERCC5 (0.50) | ERCC5FEN1HSD11B1ALDH1A1HTT | |
| SCHEMBL12173023 | 0.83 | ERCC5 (0.50) | ERCC5FEN1HSD11B1ALDH1A1HTT | |
| SCHEMBL12697045 | 0.83 | P2RX7 (0.44) | ERCC5FEN1HSD11B1ALDH1A1HDAC6 | |
| SCHEMBL6850685 | 0.82 | ERCC5 (0.49) | ERCC5FEN1HSD11B1ALDH1A1HTT | |
| SCHEMBL6849951 | 0.82 | ALDH1A1 (0.47) | ERCC5FEN1HSD11B1ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8530506-B2 | Process for production of biphenyl derivative | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2013-09-10 | — | — | US | disclosed |
| EP-2502919-A1 | PROCESS FOR PRODUCTION OF BIPHENYL DERIVATIVE | Mitsubishi Tanabe Pharma Corporation (JP) | 2012-09-26 | — | — | EP | disclosed |
| US-20120232283-A1 | PROCESS FOR PRODUCTION OF BIPHENYL DERIVATIVE | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2012-09-13 | — | — | US | disclosed |
| WO-2011061996-A1 | PROCESS FOR PRODUCTION OF BIPHENYL DERIVATIVE | 田辺三菱製薬株式会社 (JP) | 2011-05-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120232283-A1 | PROCESS FOR PRODUCTION OF BIPHENYL DERIVATIVE | AGTR2, AGTR1, ACE | ERCC5 3866/4885FEN1 4663/4885HSD11B1 301/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.