Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 1/20 | 0.67 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.55 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.48 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | PDE2A | O00408 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21434752 | 0.89 | CFTR (0.53) | CFTRMRGPRX4PDK2ABL1KMT2A | |
| SCHEMBL3115745 | 0.87 | CFTR (0.62) | CFTRMRGPRX4CES2KMT2AMCL1 | |
| SCHEMBL28527878 | 0.86 | CFTR (0.51) | CFTRMRGPRX4PDK2PDE2ACES2 | |
| SCHEMBL2892506 | 0.85 | CFTR (0.47) | CFTRMRGPRX4PDK2ABL1KMT2A | |
| SCHEMBL4057367 | 0.85 | KDM4E (0.52) | CFTRMRGPRX4PDK2ABL1ATM | |
| SCHEMBL22263091 | 0.84 | CFTR (0.73) | CFTRMRGPRX4PDK2CES2ATM | |
| SCHEMBL21434673 | 0.83 | CFTR (0.46) | CFTRMRGPRX4PDK2ABL1KMT2A | |
| SCHEMBL167426 | 0.83 | CFTR (0.71) | CFTRMRGPRX4PDK2CES2ATM | |
| SCHEMBL6849228 | 0.83 | MRGPRX4 (0.59) | CFTRMRGPRX4KMT2AKDM4EMEN1 | |
| SCHEMBL2002005 | 0.81 | CFTR (0.69) | CFTRMRGPRX4PDK2CES2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104926702-A | Preparation method for 2-methylmercapto-4-thrifluoromethyl benzoate | HUNAN HAILI CHEMICAL INDUSTRY CO LTD | 2015-09-23 | — | — | CN | disclosed |
| CN-1176071-C | Process for preparation of 2-alkylthio benzoic acid derivatives | ����-���ʿ�ũҵ��˾ | 2004-11-17 | — | — | CN | disclosed |
| US-6777575-B2 | BY REACTING AN ALKYLMERCAPTAN WITH THE CORRESPONDING 2-HALO OR 2-NITRO BENZOIC ACID DERIVATIVE; USEFUL AS INTERMEDIATES TO HERBICIDES | RHONE-POULENC AGRO (FR) | 2004-08-17 | — | — | US | disclosed |
| CN-1135210-C | Process for preparation of 1-aryl-3-cyclopropyl-1,3-propanediones | ����-���ʿ�ũҵ��˾ | 2004-01-21 | — | — | CN | disclosed |
| EP-0994840-B1 | PROCESS FOR THE PREPARATION OF 1-ARYL-3-CYCLOPROPYL-1,3-PROPANEDIONES | BAYER CROPSCIENCE SA (FR) | 2003-05-14 | — | — | EP | disclosed |
| US-6486356-B2 | REACTINBG AN ARONATIC ESTER WITH CYCLOPROPYL METHYL KETONE | RHONE-POULENC AGRO (FR) | 2002-11-26 | — | — | US | disclosed |
| US-20020103396-A1 | PROCESS FOR THE PREPARATION OF 2-ALKYLTHIO BENZOIC ACID DERIVATIVES | RHONE-POULENC AGRO (FR) | 2002-08-01 | — | — | US | disclosed |
| US-20020002309-A1 | PROCESS FOR THE PREPARATION OF 1-ARYL-3-CYCLOPROPYL-1,3-PROPANEDIONES | RHONE-POULENC AGRO (FR) | 2002-01-03 | — | — | US | disclosed |
| CN-1262670-A | Preparation method of 1-aryl-3-cyclopropyl-1, 3-propanedione | RHONE POULENC AGROCHIMIE (FR) | 2000-08-09 | — | — | CN | disclosed |
| CN-1262673-A | Process for preparation of 2-alkylthio benzoic acid derivatives | RHONE POULENC AGROCHIMIE (FR) | 2000-08-09 | — | — | CN | disclosed |
| US-5744021-A | 2-alkylmercapto-4-(trifluoromethyl)benzoic esters and a process for their preparation | HOECHST AG (DE) | 1998-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020103396-A1 | PROCESS FOR THE PREPARATION OF 2-ALKYLTHIO BENZOIC ACID DERIVATIVES | HAX1, BRIX1, SFXN1 | CFTR 1260/4885MRGPRX4 370/4885PDK2 3247/4885 |
| US-20020002309-A1 | PROCESS FOR THE PREPARATION OF 1-ARYL-3-CYCLOPROPYL-1,3-PROPANEDIONES | CYP1B1, CYP11B1, ADH1C | CFTR 747/4885MRGPRX4 3159/4885PDK2 190/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.