Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 4/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6615162 | 0.86 | CHRM2 (0.42) | HTR2CGLATACR1LMNA | |
| SCHEMBL27372387 | 0.80 | TSHR (0.54) | HTR2CGLATSHR | |
| SCHEMBL6040251 | 0.76 | GRM5 (0.39) | HTR2CGRM5TACR1LMNATSHR | |
| SCHEMBL28514239 | 0.76 | GLA (0.44) | HTR2CGLATSHR | |
| SCHEMBL12479526 | 0.75 | GLA (0.43) | HTR2CGLAHTR2BLMNATSHR | |
| SCHEMBL17070 | 0.72 | LTA4H (0.61) | LTA4HTACR1LMNATSHRBCHE | |
| SCHEMBL6299585 | 0.72 | LTA4H (0.61) | LTA4HTACR1LMNATSHRBCHE | |
| SCHEMBL17069 | 0.72 | LTA4H (0.61) | LTA4HTACR1LMNATSHRBCHE | |
| SCHEMBL17144545 | 0.71 | MC4R (0.63) | HTR2CHTR2BTSHR | |
| Phenol SCHEMBL28709666 | 0.71 | CNR2 (0.41) | GLATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0874852-B1 | OXAZOLIDINONE ANTIBACTERIAL AGENT WITH TRICYCLIC SUBSTITUENTS | UPJOHN CO (US) | 2004-03-31 | — | — | EP | disclosed |