Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 4/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.35 |
| ▸ | MC4R | P32245 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3553273 | 0.82 | FAAH (0.42) | MC4R | |
| SCHEMBL5761025 | 0.81 | HTR2C (0.46) | HTR2CLMNATSHR | |
| SCHEMBL6848128 | 0.76 | HTR2C (0.43) | GRM5HTR2CLMNATSHRTACR1 | |
| SCHEMBL8656130 | 0.72 | NAAA (0.39) | NPC1LMNATSHR | |
| SCHEMBL6040299 | 0.72 | — | — | |
| SCHEMBL4839660 | 0.71 | REN (0.43) | LMNATSHRTACR1 | |
| SCHEMBL2569683 | 0.71 | KMT2A (0.39) | TSHR | |
| SCHEMBL8654249 | 0.71 | SMN1; SMN2 (0.45) | NPC1LMNA | |
| SCHEMBL10702694 | 0.71 | NAAA (0.47) | NPC1LMNA | |
| SCHEMBL8654542 | 0.70 | NAAA (0.49) | NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7049443-B2 | Amide-containing compound having improved solubility and method of improving the solubility of an amide-containing compound | PHARMACIA & UPJOHN COMPANY (US) | 2006-05-23 | — | — | US | disclosed |