Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 20/20 | 0.64 |
| ▸ | BCHE | P06276 | 9/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6989427 | 0.91 | ACHE (0.62) | ACHEBCHE | |
| SCHEMBL6986573 | 0.90 | ACHE (0.72) | ACHEBCHE | |
| SCHEMBL6989899 | 0.86 | ACHE (0.72) | ACHEBCHE | |
| SCHEMBL7672658 | 0.84 | ACHE (0.65) | ACHEBCHE | |
| SCHEMBL7674312 | 0.82 | ACHE (0.71) | ACHEBCHE | |
| Icopezil SCHEMBL194482 | 0.78 | ACHE (1.00) | ACHEBCHE | |
| Icopezil SCHEMBL3339253 | 0.77 | ACHE (1.00) | ACHEBCHE | |
| Icopezil SCHEMBL2231222 | 0.77 | ACHE (1.00) | ACHEBCHE | |
| SCHEMBL2405514 | 0.77 | ACHE (0.84) | ACHEBCHE | |
| SCHEMBL2403486 | 0.75 | ACHE (0.82) | ACHEBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0788500-B1 | PROCESSES AND INTERMEDIATES FOR PREPARING 5,7-DIHYDRO-3- 2- 1-BENZYLPIPERIDIN-4-YL ETHYL]-6H-PYRROLO- 4,5-f]-1,2-BENZISOXAZOL-6-ONE | PFIZER (US) | 2004-03-03 | — | — | EP | disclosed |
| US-5916902-A | Processes and intermediates for preparing 5, 7-dihydro-3- 2-(1-benzylpiperidin-4-yl)ethyl-!6H-pyrrolo- 4, 5-F!-1, 2-benzisoxazol-6-one | PFIZER INC. (US) | 1999-06-29 | — | — | US | disclosed |
| WO-1996013505-A1 | PROCESSES AND INTERMEDIATES FOR PREPARING 5,7-DIHYDRO-3-[2-{1-BENZYLPIPERIDIN-4-YL}ETHYL]-6H-PYRROLO-[4,5-f]-1,2-BENZISOXAZOL-6-ONE | PFIZER INC. (US) | 1996-05-09 | — | — | WO | disclosed |