SCHEMBL6848307

SCHEMBL6848307

Nc1ccc(O[C]=O)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.50
TDP1 Q9NUW8 6/20 0.50
CYP3A4 P08684 3/20 0.50
TSHR P16473 2/20 0.50
MAPK1 P28482 2/20 0.46
MAOA P21397 3/20 0.42
MAPT P10636 6/20 0.42
MEN1 O00255 3/20 0.42
KMT2A Q03164 3/20 0.42
APP P05067 2/20 0.41
MAOB P27338 2/20 0.41
TEAD4 Q15561 1/20 0.41
PARP10 Q53GL7 1/20 0.40
SMN1; SMN2 Q16637 3/20 0.39
GAA P10253 2/20 0.39
POLB P06746 1/20 0.39
MITF O75030 1/20 0.39
GFER P55789 1/20 0.39
NLRP1 Q9C000 1/20 0.39
NOD2 Q9HC29 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8142070 0.86 CA2 (0.32)
SCHEMBL96632 0.74 MEN1 (0.43) ALDH1A1TDP1CYP3A4MAPK1MAOA
SCHEMBL95901 0.74 ACHE (0.48) ALDH1A1TDP1CYP3A4TSHRMAPT
SCHEMBL95869 0.74 SOS1 (0.39) ALDH1A1APPMAOB
SCHEMBL7937190 0.74 ALDH1A1 (0.50) ALDH1A1TDP1CYP3A4TSHRMAPK1
SCHEMBL4867495 0.74 MEN1 (0.50) ALDH1A1CYP3A4MAPTMEN1KMT2A
SCHEMBL96667 0.74 CA1 (0.58) ALDH1A1TDP1CYP3A4MAPK1MAPT
SCHEMBL7003904 0.74 CA1 (0.43) APP
SCHEMBL97751 0.74 CA2 (0.43) ALDH1A1TSHRMAPK1MAOAMAPT
SCHEMBL7295640 0.73 NR4A1 (0.56) ALDH1A1TDP1CYP3A4TSHRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118302199-A Anti-CDH 6 antibodies and antibody-drug conjugates thereof 普众发现医药科技(上海)有限公司 2024-07-05 CN claimed
WO-2024083162-A1 ANTIBODIES, ANTIBODY-DRUG CONJUGATES, PREPARATIONS AND USES THEREOF MULTITUDE THERAPEUTICS INC. (CN) 2024-04-25 WO claimed
WO-2023104188-A1 ANTI-CDH6 ANTIBODIES AND ANTIBODY-DRUG CONJUGATES THEREOF MULTITUDE THERAPEUTICS INC. (CN) 2023-06-15 WO claimed
WO-2023102875-A1 ANTI-CDH6 ANTIBODY DRUG CONJUGATE MULTITUDE THERAPEUTICS INC. (CN) 2023-06-15 WO claimed
EP-0799827-B1 ACRYLAMIDE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME KYORIN SEIYAKU KK (JP) 2004-05-12 EP claimed
CN-118302199-A Anti-CDH 6 antibodies and antibody-drug conjugates thereof 普众发现医药科技(上海)有限公司 2024-07-05 CN disclosed
WO-2024083162-A1 ANTIBODIES, ANTIBODY-DRUG CONJUGATES, PREPARATIONS AND USES THEREOF MULTITUDE THERAPEUTICS INC. (CN) 2024-04-25 WO disclosed
CN-116438456-A Detection of in vitro protease activity for disease detection/diagnosis, staging, monitoring and treatment 格里姆普斯生物股份有限公司 2023-07-14 CN disclosed
WO-2023102875-A1 ANTI-CDH6 ANTIBODY DRUG CONJUGATE MULTITUDE THERAPEUTICS INC. (CN) 2023-06-15 WO disclosed
WO-2023104188-A1 ANTI-CDH6 ANTIBODIES AND ANTIBODY-DRUG CONJUGATES THEREOF MULTITUDE THERAPEUTICS INC. (CN) 2023-06-15 WO disclosed
CN-114514041-A anti-PTCRA antibody-drug conjugates and uses thereof 瑞泽恩制药公司 2022-05-17 CN disclosed
CN-114245802-A Modified IL-2 proteins, PEG conjugates and uses thereof 石药集团巨石生物制药有限公司 2022-03-25 CN disclosed
WO-1997008193-A1 ACYLATED OLIGOPEPTIDE DERIVATIVES HAVING CELL SIGNAL INHIBITING ACTIVITY NOVARTIS AG (CH) 1997-03-06 WO disclosed
US-5436254-A Vaopressin antagonists OTSUKA PHARMACEUTICAL COMPANY, LTD. (JP) 1995-07-25 US disclosed
EP-0602209-A1 OXYTOCIN ANTAGONIST OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1994-06-22 EP disclosed
EP-0382185-B1 Carbostyril derivatives OTSUKA PHARMA CO LTD (JP) 1994-06-15 EP disclosed
WO-1994001113-A1 OXYTOCIN ANTAGONIST OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) 1994-01-20 WO disclosed
US-5225402-A Vasopressin antagonist, vasodilation, hypotensive, diuretics and anticoagulants OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1993-07-06 US disclosed
EP-0409117-A1 Silver halide photographic material KONICA CORPORATION (JP) 1991-01-23 EP disclosed
EP-0382185-A2 Carbostyril derivatives OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1990-08-16 EP disclosed