SCHEMBL4867495

SCHEMBL4867495

O=[C]Oc1ccc(O)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.50
KMT2A Q03164 3/20 0.50
ESR2 Q92731 2/20 0.50
ESR1 P03372 2/20 0.50
LTA4H P09960 3/20 0.42
NR1H2 P55055 1/20 0.42
BAX Q07812 1/20 0.42
KDM4E B2RXH2 2/20 0.42
LMNA P02545 2/20 0.42
HIF1A Q16665 2/20 0.42
NPC1 O15118 1/20 0.42
CA12 O43570 1/20 0.42
GMNN O75496 1/20 0.42
ALDH1A1 P00352 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA3 P07451 1/20 0.42
CYP3A4 P08684 1/20 0.42
MAPT P10636 1/20 0.42
TYR P14679 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8142070 0.86 CA2 (0.32) CA12CA1CA2CA9CA14
SCHEMBL9785165 0.78 NPC1 (0.56) MEN1KMT2AKDM4ELMNANPC1
SCHEMBL7003904 0.74 CA1 (0.43) LTA4HCA12CA1CA2CA9
SCHEMBL97751 0.74 CA2 (0.43) MEN1KMT2ALMNAALDH1A1CA1
SCHEMBL11707143 0.74 ESR2 (0.50) MEN1KMT2AESR2ESR1LTA4H
SCHEMBL96667 0.74 CA1 (0.58) LTA4HKDM4ENPC1CA12ALDH1A1
SCHEMBL95869 0.74 SOS1 (0.39) ALDH1A1CA1CA2CA9APP
SCHEMBL96632 0.74 MEN1 (0.43) MEN1KMT2ALTA4HLMNAALDH1A1
SCHEMBL95901 0.74 ACHE (0.48) MEN1KMT2ALMNAALDH1A1CA1
SCHEMBL6848307 0.74 ALDH1A1 (0.50) MEN1KMT2ANPC1ALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2495234-B1 AROMATIC SULFONIUM SALT COMPOUND ADEKA CORP (JP) 2018-06-06 EP disclosed
CN-102510856-B Aromatic sulfonium salt compound ADEKA CORP. (JP) 2015-08-05 CN disclosed
US-9073854-B2 Aromatic sulfonium salt compound ADEKA CORPORATION (JP) 2015-07-07 US disclosed
CN-102471255-B Aromatic sulfonium salt compound ADEKA CORP 2015-06-03 CN disclosed
EP-2502915-B1 AROMATIC SULFONIUM SALT COMPOUND ADEKA CORP (JP) 2015-03-18 EP disclosed
EP-2502915-A1 AROMATIC SULFONIUM SALT COMPOUND Adeka Corporation (JP) 2012-09-26 EP disclosed
EP-2495234-A1 AROMATIC SULFONIUM SALT COMPOUND Adeka Corporation (JP) 2012-09-05 EP disclosed
CN-102510856-A Aromatic sulfonium salt compound ADEKA CORP 2012-06-20 CN disclosed
US-20120136155-A1 AROMATIC SULFONIUM SALT COMPOUND ADEKA CORPORATION (JP) 2012-05-31 US disclosed
US-20120130117-A1 AROMATIC SULFONIUM SALT COMPOUND ADEKA CORPORATION (JP) 2012-05-24 US disclosed
US-5635534-A 1-PHENYL-2-(2-PHENYLOXY OR THIO)-1-METHYLETHYL)AMINOETHANOL DERIVATIVES; ALDOSE REDUCTASE INHIBITORS; NONTOXIC; ANTIDIABETIC,-OBESITY,-LIPEMIC AND HYPOGLYCEMIC AGENTS SANKYO COMPANY, LIMITED (JP) 1997-06-03 US disclosed
US-5616446-A Silver halide photographic light-sensitive material KONICA CORPORATION (JP) 1997-04-01 US disclosed
US-5576340-A Aromatic amino-alcohol derivatives having anti-diabetic and anti-obesity properties, their preparation and their therapeutic uses SANKYO COMPANY, LIMITED (JP) 1996-11-19 US disclosed
US-5541047-A IMIDAZOLE OR OXAZOLE CYANINE DYES AS SENSITIZERS KONICA CORPORATION (JP) 1996-07-30 US disclosed
EP-0704757-A1 A silver halide photographic light sensitive material KONICA CORPORATION (JP) 1996-04-03 EP disclosed
EP-0658805-A2 A silver halide photographic emulsion, a silver halide photographic light-sensitive material and a method for processing the same KONICA CORPORATION (JP) 1995-06-21 EP disclosed
EP-0215124-B1 SILVER HALIDE PHOTOGRAPHIC PHOTO-SENSITIVE MATERIAL FUJI PHOTO FILM CO., LTD. (JP) 1991-09-04 EP disclosed
US-4925782-A Silver halide photographic light-sensitive element containing water soluble dye compounds FUJI PHOTO FILM CO., LTD. (JP) 1990-05-15 US disclosed
US-4879204-A HIGH CONTRAST FUJI PHOTO FILM CO., LTD. (JP) 1989-11-07 US disclosed
EP-0215124-A1 SILVER HALIDE PHOTOGRAPHIC PHOTO-SENSITIVE MATERIAL FUJI PHOTO FILM CO., LTD. (JP) 1987-03-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120136155-A1 AROMATIC SULFONIUM SALT COMPOUND F12, ASIC1, SPIN1 MEN1 1116/4885KMT2A 1571/4885ESR2 3455/4885
US-20120130117-A1 AROMATIC SULFONIUM SALT COMPOUND SLC6A19, ARSA, PAH MEN1 3308/4885KMT2A 1675/4885ESR2 2954/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.