Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 13/20 | 0.54 |
| ▸ | CTSB | P07858 | 5/20 | 0.44 |
| ▸ | CTSL | P07711 | 5/20 | 0.44 |
| ▸ | CTSK | P43235 | 2/20 | 0.42 |
| ▸ | CTSH | P09668 | 1/20 | 0.42 |
| ▸ | CTSC | P53634 | 1/20 | 0.42 |
| ▸ | TACR2 | P21452 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6848124 | 0.89 | CTSS (0.55) | CTSSCTSBCTSLCTSKCTSH | |
| SCHEMBL6848372 | 0.84 | CTSS (0.52) | CTSSCTSBCTSLCTSK | |
| SCHEMBL14491119 | 0.84 | CTSS (0.52) | CTSSCTSBCTSLCTSK | |
| SCHEMBL3023908 | 0.83 | CTSS (0.57) | CTSSCTSBCTSLCTSKCTSH | |
| SCHEMBL3023913 | 0.83 | CTSS (0.57) | CTSSCTSBCTSLCTSKCTSH | |
| SCHEMBL5438934 | 0.83 | CTSS (0.57) | CTSSCTSBCTSLCTSKCTSH | |
| SCHEMBL6848129 | 0.83 | CTSS (0.53) | CTSSCTSBCTSLCTSKCTSH | |
| SCHEMBL6560100 | 0.83 | CTSS (0.53) | CTSSCTSBCTSLCTSKCTSH | |
| SCHEMBL14565773 | 0.82 | CTSS (0.52) | CTSSCTSBCTSLCTSKCTSH | |
| SCHEMBL6847753 | 0.81 | CTSS (0.49) | CTSSCTSBCTSLCTSKCTSH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070135386-A1 | Novel Compounds and Compositions as Cathepsin Inhibitors | AVENTIS PHARMACEUTICALS INC. (US) | 2007-06-14 | — | — | US | disclosed |
| US-20070135386-A1 | Novel Compounds and Compositions as Cathepsin Inhibitors | AVENTIS PHARMACEUTICALS INC. (US) | 2007-06-14 | — | — | US | disclosed |
| US-7196099-B2 | Compounds and compositions as cathepsin inhibitors | AVENTIS PHARMACEUTICALS INC. (US) | 2007-03-27 | — | — | US | disclosed |
| US-7196099-B2 | Compounds and compositions as cathepsin inhibitors | AVENTIS PHARMACEUTICALS INC. (US) | 2007-03-27 | — | — | US | disclosed |
| US-20040192742-A1 | Novel compounds and compositions as cathepsin inhibitors | AVENTIS PHARMACEUTICALS INC. | 2004-09-30 | — | — | US | disclosed |
| US-6696600-B2 | NONHYGROSCOPIC, CRYSTALLINE MONO- OR DICARBOXYLIC ACID DERIVATIVE | TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) | 2004-02-24 | — | — | US | disclosed |
| US-20030162832-A1 | L-DOPA ethyl ester salts and uses thereof | TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) | 2003-08-28 | — | — | US | disclosed |
| WO-2003041646-A2 | L-DOPA ETHYL ESTER SALTS AND USES THEREOF | TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) | 2003-05-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040192742-A1 | Novel compounds and compositions as cathepsin inhibitors | CTSS, CTSB, CTSE | CTSS 1/4885CTSB 2/4885CTSL 11/4885 |
| US-20070135386-A1 | Novel Compounds and Compositions as Cathepsin Inhibitors | CTSS, CTSB, CTSE | CTSS 1/4885CTSB 2/4885CTSL 11/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.