SCHEMBL6848412

SCHEMBL6848412

O=C(O)c1ccc(-c2ccc(C(=O)Nc3ccc(O)cc3)c(C(=O)Nc3ccc(O)cc3)c2)cc1C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.53
NQO2 P16083 1/20 0.51
DEGS1 O15121 2/20 0.50
LMNA P02545 1/20 0.49
DDX3X O00571 1/20 0.47
GRIK1 P39086 1/20 0.47
DHODH Q02127 1/20 0.47
CYP1A2 P05177 1/20 0.47
SNCA P37840 1/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
POLB P06746 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
KMT2A Q03164 4/20 0.45
MEN1 O00255 3/20 0.45
SMO Q99835 1/20 0.44
PKM P14618 1/20 0.44
GFER P55789 2/20 0.44
KDM4E B2RXH2 1/20 0.44
MAPT P10636 1/20 0.44
HPGD P15428 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6852794 1.00 ALDH1A1 (0.53) ALDH1A1NQO2DEGS1LMNADDX3X
SCHEMBL6852854 0.97 NQO2 (0.54) ALDH1A1NQO2DEGS1LMNADDX3X
SCHEMBL6852760 0.88 ALDH1A1 (0.53) ALDH1A1DHODHCYP1A2POLBTDP1
SCHEMBL6848464 0.88 ALDH1A1 (0.53) ALDH1A1DHODHCYP1A2POLBTDP1
SCHEMBL7070052 0.87 CFD (0.45) ALDH1A1LMNAL3MBTL1POLBTDP1
SCHEMBL6852793 0.87 LMNA (0.59) ALDH1A1NQO2DEGS1LMNAGRIK1
SCHEMBL23080512 0.87 ALDH1A1 (0.71) ALDH1A1LMNADHODHCYP1A2L3MBTL1
SCHEMBL9155837 0.87 LMNA (0.58) ALDH1A1NQO2DEGS1LMNAGRIK1
SCHEMBL9164922 0.87 LMNA (0.58) ALDH1A1NQO2DEGS1LMNAGRIK1
SCHEMBL6851324 0.84 KMT2A (0.56) ALDH1A1DHODHPOLBTDP1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6828408-B2 Small coefficient of linear expansion and small water absorbing property, and excellent heat resistance; thermotropic liquid crystalline polymer for engineering plastics SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-12-07 US disclosed
US-20030083459-A1 Aromatic polyimide ester and method for producing thereof SUMITOMO CHEMICAL COMPANY, LIMITED 2003-05-01 US disclosed