SCHEMBL6848435

SCHEMBL6848435

O=C(O)c1cccc(NC(=O)c2ccc(-c3ccc(C(=O)Nc4cccc(C(=O)O)c4)c(C(=O)O)c3)cc2C(=O)O)c1

nearest known ligand 0.63

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.63
KMT2A Q03164 5/20 0.63
NPC1 O15118 5/20 0.57
RAB9A P51151 5/20 0.57
SMN1; SMN2 Q16637 5/20 0.57
HTT P42858 1/20 0.57
HPSE Q9Y251 1/20 0.56
ALDH1A1 P00352 4/20 0.55
SORT1 Q99523 1/20 0.53
PKM P14618 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
NR1H4 Q96RI1 2/20 0.52
MIF P14174 1/20 0.52
KCNK3 O14649 1/20 0.51
KCNK9 Q9NPC2 1/20 0.51
CA12 O43570 1/20 0.51
CA2 P00918 1/20 0.51
CA9 Q16790 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6852858 0.97 MEN1 (0.60) MEN1KMT2ANPC1RAB9ASMN1; SMN2
SCHEMBL6852782 0.94 HPSE (0.62) MEN1KMT2ANPC1RAB9ASMN1; SMN2
SCHEMBL6855624 0.92 HPSE (0.59) MEN1KMT2ANPC1RAB9ASMN1; SMN2
SCHEMBL29204765 0.91 HPSE (0.63) MEN1KMT2ANPC1RAB9ASMN1; SMN2
SCHEMBL6852588 0.89 RAB9A (0.60) MEN1KMT2ANPC1RAB9ASMN1; SMN2
SCHEMBL6852686 0.88 RAB9A (0.66) MEN1KMT2ANPC1RAB9ASMN1; SMN2
SCHEMBL9161426 0.87 MEN1 (0.66) MEN1KMT2ANPC1RAB9ASMN1; SMN2
SCHEMBL9164792 0.87 MEN1 (0.66) MEN1KMT2ANPC1RAB9ASMN1; SMN2
SCHEMBL2058337 0.86 ALDH1A1 (0.71) MEN1KMT2ANPC1RAB9ASMN1; SMN2
SCHEMBL13964393 0.85 SORT1 (0.65) MEN1KMT2ANPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6828408-B2 Small coefficient of linear expansion and small water absorbing property, and excellent heat resistance; thermotropic liquid crystalline polymer for engineering plastics SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-12-07 US disclosed
US-20030083459-A1 Aromatic polyimide ester and method for producing thereof SUMITOMO CHEMICAL COMPANY, LIMITED 2003-05-01 US disclosed