Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MPO | P05164 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6361123 | 0.81 | L3MBTL1 (0.58) | P2RX7ALDH1A1POLBHTTHDAC6 | |
| SCHEMBL4403732 | 0.78 | P2RX7 (0.81) | P2RX7ALDH1A1POLBHTTHDAC6 | |
| SCHEMBL6357061 | 0.78 | P2RX7 (0.56) | P2RX7ALDH1A1POLBHTTHDAC6 | |
| SCHEMBL10631244 | 0.78 | P2RX7 (0.54) | P2RX7ALDH1A1POLBHTTHDAC6 | |
| SCHEMBL6362759 | 0.76 | P2RX7 (0.75) | P2RX7KCNMA1 | |
| SCHEMBL5651126 | 0.76 | ALDH1A1 (0.62) | P2RX7ALDH1A1POLBHTTHDAC6 | |
| SCHEMBL6357253 | 0.75 | POLB (0.78) | P2RX7ALDH1A1POLBHTTHDAC6 | |
| SCHEMBL10635287 | 0.73 | ALDH1A1 (0.68) | P2RX7ALDH1A1POLBHTTHDAC6 | |
| SCHEMBL1520494 | 0.73 | HSD11B1 (0.58) | P2RX7ALDH1A1POLBHTTHDAC6 | |
| SCHEMBL6362202 | 0.73 | P2RX7 (0.68) | P2RX7ALDH1A1POLBHTTHDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2502919-A1 | PROCESS FOR PRODUCTION OF BIPHENYL DERIVATIVE | Mitsubishi Tanabe Pharma Corporation (JP) | 2012-09-26 | — | — | EP | disclosed |
| WO-2011061996-A1 | PROCESS FOR PRODUCTION OF BIPHENYL DERIVATIVE | 田辺三菱製薬株式会社 (JP) | 2011-05-26 | — | — | WO | disclosed |