SCHEMBL6848565

SCHEMBL6848565

Cc1c(O)ccc(N)c1NCCO

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.35
KDM4E B2RXH2 5/20 0.35
GAA P10253 3/20 0.35
POLB P06746 3/20 0.35
LMNA P02545 3/20 0.35
GLA P06280 2/20 0.35
RAB9A P51151 2/20 0.35
MITF O75030 1/20 0.35
TTR P02766 1/20 0.35
RAD52 P43351 1/20 0.35
ALOX15 P16050 2/20 0.34
HSD17B10 Q99714 2/20 0.34
HPGD P15428 1/20 0.34
MAPK1 P28482 5/20 0.33
ESR1 P03372 4/20 0.33
MEN1 O00255 4/20 0.33
KMT2A Q03164 4/20 0.33
USP2 O75604 3/20 0.33
ESR2 Q92731 2/20 0.33
MAPT P10636 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL456751 0.86 ALDH1A1 (0.35) ALDH1A1KDM4EGAAPOLBLMNA
SCHEMBL3164732 0.76 MAOB (0.39) ALDH1A1KDM4EPOLBHSD17B10MAPK1
SCHEMBL3666211 0.72 POLB (0.46) ALDH1A1KDM4EGAAPOLBLMNA
SCHEMBL27571552 0.71 KMT2A (0.41) ALDH1A1KDM4EGAAPOLBLMNA
Hydrochloric Acid SCHEMBL9012929 0.71 KDM4E (0.44) ALDH1A1KDM4EGAAPOLBLMNA
SCHEMBL309355 0.69 KDM4E (0.38) ALDH1A1KDM4EGAAPOLBLMNA
SCHEMBL27129462 0.69 ALDH1A1 (0.36) ALDH1A1KDM4EGAAPOLBLMNA
SCHEMBL28478567 0.68 ALDH1A1 (0.38) ALDH1A1KDM4EGAAPOLBRAB9A
SCHEMBL1383429 0.68 POLB (0.42) ALDH1A1KDM4EGAAPOLBLMNA
SCHEMBL7177433 0.68 NAAA (0.42) ALDH1A1KDM4ELMNARAB9AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12337052-B2 Hair treatment method that increases the bond density of damaged hair BEAUTY & BUSINESS S.P.A. (IT) 2025-06-24 US disclosed
US-20240033199-A1 HAIR TREATMENT METHOD THAT INCREASES THE BOND DENSITY OF DAMAGED HAIR BEAUTY & BUSINESS S.P.A. (IT) 2024-02-01 US disclosed
EP-4309742-A1 HAIR TREATMENT METHOD THAT INCREASES THE BOND DENSITY OF DAMAGED HAIR Beauty & Business S.p.A. (IT) 2024-01-24 EP disclosed
CN-117426992-A Hair treatment method for increasing bond density of damaged hair 美容与商业股份有限公司 2024-01-23 CN disclosed
CN-1216591-C Colorant for dyeing keratin fibers HENKEL KGAA (DE) 2005-08-31 CN disclosed
US-6773463-B2 A MIXTURE OF A 4-NITRO-2,1,3-BENZOXADIAZOLE, A 4-NITRO-2,1,3-BENZOTHIADIAZOLE, OR A 4-NITRO-2,1,3-BENZO-SELENADIAZOLE AND AT LEAST ONE AMINE, PHENOL, OR AMINONITROBENZENE; INTENSE COLORATIONS; MILD CONDITIONS; DIRECT HAIR DYE WELLA AKTIENGESELLSCHAFT (DE) 2004-08-10 US disclosed
US-20030070239-A1 Agent and method for dyeing keratin fibers HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) 2003-04-17 US disclosed
CN-1306415-A Colorant for colouring keratin fibres HENKEL KGAA (DE) 2001-08-01 CN disclosed
CN-1270511-A Extract and cosmetic preparation HENKEL KGAA (DE) 2000-10-18 CN disclosed
CN-1268047-A Preservative system for personal hygiene products HENKEL KGAA (DE) 2000-09-27 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030070239-A1 Agent and method for dyeing keratin fibers KRT18, AOC1, S100B ALDH1A1 87/4885KDM4E 1476/4885GAA 4684/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.