Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 4/20 | 0.76 |
| ▸ | MMP12 | P39900 | 2/20 | 0.76 |
| ▸ | GAA | P10253 | 1/20 | 0.76 |
| ▸ | MMP2 | P08253 | 10/20 | 0.69 |
| ▸ | MMP9 | P14780 | 8/20 | 0.69 |
| ▸ | MMP7 | P09237 | 4/20 | 0.69 |
| ▸ | MMP14 | P50281 | 4/20 | 0.69 |
| ▸ | MMP3 | P08254 | 3/20 | 0.69 |
| ▸ | MMP13 | P45452 | 3/20 | 0.69 |
| ▸ | MEP1B | Q16820 | 3/20 | 0.69 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.69 |
| ▸ | MMP8 | P22894 | 1/20 | 0.69 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.61 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.51 |
| ▸ | IKBKB | O14920 | 1/20 | 0.50 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2969958 | 0.90 | MMP1 (0.59) | MMP1MMP12GAAMMP2MMP9 | |
| SCHEMBL10890150 | 0.86 | MMP1 (1.00) | MMP1MMP12GAAMMP2MMP9 | |
| SCHEMBL6271017 | 0.86 | MMP1 (0.80) | MMP1MMP12GAAMMP2MMP9 | |
| SCHEMBL3142362 | 0.81 | HDAC1 (0.70) | MMP1MMP12GAAMMP2MMP9 | |
| SCHEMBL13723973 | 0.81 | CA1 (0.65) | MMP1MMP2MMP9MMP13MMP8 | |
| SCHEMBL21067576 | 0.81 | MMP1 (0.71) | MMP1MMP12GAAMMP2MMP9 | |
| SCHEMBL6850069 | 0.79 | MEP1B (0.62) | MMP1GAAMMP2MMP9MMP14 | |
| SCHEMBL20743688 | 0.79 | MMP1 (0.66) | MMP1MMP12GAAMMP2MMP9 | |
| SCHEMBL4859251 | 0.79 | ALDH1A1 (0.61) | MMP1MMP2MMP9MMP13MMP8 | |
| SCHEMBL6850445 | 0.79 | MEP1B (0.62) | MMP1MMP2MMP9MMP13MEP1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774212-B2 | FOR THERAPY OF VIRAL INFECTION OR AS AN ASSAY STANDARD OR REAGENT | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2004-08-10 | — | — | US | disclosed |