Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEP1B | Q16820 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | MMP1 | P03956 | 2/20 | 0.57 |
| ▸ | CA1 | P00915 | 4/20 | 0.53 |
| ▸ | CA2 | P00918 | 4/20 | 0.53 |
| ▸ | MMP2 | P08253 | 1/20 | 0.53 |
| ▸ | MMP9 | P14780 | 1/20 | 0.53 |
| ▸ | MMP8 | P22894 | 1/20 | 0.53 |
| ▸ | MMP13 | P45452 | 1/20 | 0.53 |
| ▸ | F2 | P00734 | 1/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.53 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.53 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7598374 | 0.84 | NPC1 (0.47) | MEP1BNPC1MMP1F2ALDH1A1 | |
| SCHEMBL13723973 | 0.84 | CA1 (0.65) | MMP1CA1CA2MMP2MMP9 | |
| SCHEMBL11708062 | 0.83 | MEP1B (0.68) | MEP1BMMP1CA1CA2MMP2 | |
| SCHEMBL6849946 | 0.82 | FABP4 (0.55) | MEP1BNPC1MMP1FLT1FLT4 | |
| SCHEMBL20743688 | 0.82 | MMP1 (0.66) | MEP1BMMP1CA1CA2MMP2 | |
| SCHEMBL4859251 | 0.82 | ALDH1A1 (0.61) | MMP1CA1CA2MMP2MMP9 | |
| SCHEMBL6850069 | 0.82 | MEP1B (0.62) | MEP1BMMP1CA1CA2MMP2 | |
| SCHEMBL2969958 | 0.81 | MMP1 (0.59) | MEP1BMMP1CA1CA2MMP2 | |
| SCHEMBL23014305 | 0.81 | MEP1B (0.60) | MEP1BMMP1CA1CA2MMP2 | |
| SCHEMBL6850559 | 0.80 | KAT6A (0.61) | FLT1FLT4KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102786447-A | N,N-disubstituted aryl sulfonamide compound as well as preparation method and purpose of N,N-disubstituted aryl sulfonamide compound | UNIV SICHUAN | 2012-11-21 | — | — | CN | disclosed |
| EP-2471769-A1 | Process for preparing a benzonitrile derivative | Bristol-Myers Squibb Company (US) | 2012-07-04 | — | — | EP | disclosed |
| EP-2295417-A1 | Novel intermediates useful for preparing alpha-(n-sulfonamido)acetamide compound | Bristol-Myers Squibb Company (US) | 2011-03-16 | — | — | EP | disclosed |
| WO-2009058552-A1 | A NOVEL ALPHA-(N-SULFONAMIDO)ACETAMIDE COMPOUND AS AN INHIBITOR OF BETA AMYLOID PEPTIDE PRODUCTION | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-05-07 | — | — | WO | disclosed |
| US-6774212-B2 | FOR THERAPY OF VIRAL INFECTION OR AS AN ASSAY STANDARD OR REAGENT | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2004-08-10 | — | — | US | disclosed |