Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.44 |
| ▸ | CDK4 | P11802 | 1/20 | 0.44 |
| ▸ | CCND2 | P30279 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5560042 | 0.83 | MAOA (0.64) | MAOAMAPTMAPK1RAB9AL3MBTL1 | |
| SCHEMBL9511573 | 0.79 | MAOA (0.71) | MAOAMAPTMAPK1RAB9AL3MBTL1 | |
| SCHEMBL6849240 | 0.77 | MAPT (0.58) | MAOAMAPTRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL5563589 | 0.77 | MAOA (0.55) | MAOAMAPTMAPK1RAB9AL3MBTL1 | |
| SCHEMBL6852445 | 0.76 | MAOA (0.56) | MAOAMAPTMAPK1RAB9AL3MBTL1 | |
| SCHEMBL2601918 | 0.75 | MAOA (1.00) | MAOAMAPTMAPK1RAB9AL3MBTL1 | |
| SCHEMBL28044169 | 0.74 | MAOA (0.64) | MAOAMAPTMAPK1RAB9AL3MBTL1 | |
| SCHEMBL5804633 | 0.73 | MAOA (0.68) | MAOAMAPTMAPK1RAB9AL3MBTL1 | |
| SCHEMBL20892849 | 0.73 | MAOA (0.62) | MAOAMAPTMAPK1RAB9AL3MBTL1 | |
| SCHEMBL10530825 | 0.72 | MAOA (0.66) | MAOAMAPTMAPK1RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6777564-B2 | AS ANTITUMOR AGENTS | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2004-08-17 | — | — | US | claimed |
| US-20030149092-A1 | Anthraquinone compound | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2003-08-07 | — | — | US | claimed |
| US-6777564-B2 | AS ANTITUMOR AGENTS | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2004-08-17 | — | — | US | disclosed |
| US-20030149092-A1 | Anthraquinone compound | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2003-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030149092-A1 | Anthraquinone compound | ANTXR2, AAAS, H1-0 | MAOA 2399/4885MAPT 4646/4885MAPK1 709/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.