SCHEMBL8561276

SCHEMBL8561276

NC(=O)NN1CCCCCC1=O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.40
LMNA P02545 2/20 0.36
KMT2A Q03164 1/20 0.36
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA3 P07451 1/20 0.36
CA4 P22748 1/20 0.36
CA6 P23280 1/20 0.36
CA5A P35218 1/20 0.36
CA7 P43166 1/20 0.36
CA9 Q16790 1/20 0.36
CA13 Q8N1Q1 1/20 0.36
CA14 Q9ULX7 1/20 0.36
CA5B Q9Y2D0 1/20 0.36
MITF O75030 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
MAPK1 P28482 1/20 0.34
ALDH1A1 P00352 2/20 0.33
HPGD P15428 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6849692 0.92 TSHR (0.47) TSHRLMNAKMT2ACA12CA1
SCHEMBL11656190 0.85 TSHR (0.38) TSHRLMNAKMT2ACA12CA1
SCHEMBL3350811 0.84 KMT2A (0.40) TSHRLMNAKMT2AMITFSMN1; SMN2
SCHEMBL909148 0.82 KMT2A (0.37) TSHRLMNAKMT2AMITFSMN1; SMN2
SCHEMBL28641863 0.78 CRBN (0.35) ALDH1A1KDM4EGAAPOLB
SCHEMBL28464884 0.77 TSHR (0.35) TSHRLMNAKMT2AMITFSMN1; SMN2
SCHEMBL23077180 0.77 HDAC1 (0.40) LMNAKMT2ASMN1; SMN2MAPK1ALDH1A1
SCHEMBL1272614 0.76 ALDH1A1 (0.37) LMNAKMT2AMITFSMN1; SMN2ALDH1A1
SCHEMBL27917088 0.76 TGM2 (0.38) TSHRLMNAKMT2A
SCHEMBL10920232 0.75 LMNA (0.41) TSHRLMNAKMT2ACA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0830421-A1 MODIFIED AMINO CROSSLINKING AGENTS CYTEC TECHNOLOGY CORP. (US) 1998-03-25 EP claimed
US-5665852-A USEFUL IN POWDER COATING COMPOSITIONS CYTEC TECHNOLOGY CORP. (US) 1997-09-09 US claimed
WO-1996040825-A1 MODIFIED AMINO CROSSLINKING AGENTS CYTEC TECHNOLOGY CORP. (US) 1996-12-19 WO claimed
EP-0830421-A1 MODIFIED AMINO CROSSLINKING AGENTS CYTEC TECHNOLOGY CORP. (US) 1998-03-25 EP disclosed
US-5665852-A USEFUL IN POWDER COATING COMPOSITIONS CYTEC TECHNOLOGY CORP. (US) 1997-09-09 US disclosed
WO-1996040825-A1 MODIFIED AMINO CROSSLINKING AGENTS CYTEC TECHNOLOGY CORP. (US) 1996-12-19 WO disclosed
US-5527797-A IONTOPHORESIS MACROCHEM CORPORATION (US) 1996-06-18 US disclosed