Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.37 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30640643 | 0.65 | — | — | |
| SCHEMBL16075134 | 0.58 | CRBN (0.47) | CRBN | |
| SCHEMBL4905025 | 0.58 | CXCR4 (0.35) | — | |
| Hydrochloric Acid SCHEMBL19212616 | 0.58 | KDM4E (0.36) | — | |
| SCHEMBL4903063 | 0.56 | ALDH1A1 (0.41) | — | |
| 2-Pyrrolidone SCHEMBL27827832 | 0.56 | — | — | |
| 2-Pyrrolidone SCHEMBL2167448 | 0.56 | OR51E2 (1.00) | OR51E2CRBNFKBP5 | |
| 2-Pyrrolidone SCHEMBL4299593 | 0.56 | — | — | |
| 2-Pyrrolidone SCHEMBL9304498 | 0.56 | OR51E2 (1.00) | OR51E2CRBNFKBP5 | |
| 2-Pyrrolidone SCHEMBL2389 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2289882-A1 | 3-oxopiperazinium derivatives as agonists of nerve growth factor and their use as medicaments | Institut d'Investigacions Biomédiques August PI I Sunyer (ES) | 2011-03-02 | — | — | EP | disclosed |