SCHEMBL685016

SCHEMBL685016

Cc1ccc(C(=O)N/N=C/c2ccc(Cl)cc2O)cc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.66
KDM1A O60341 2/20 0.64
KMT2A Q03164 5/20 0.62
MEN1 O00255 4/20 0.62
RAB9A P51151 4/20 0.62
KDM4E B2RXH2 3/20 0.62
LMNA P02545 2/20 0.62
HTT P42858 2/20 0.62
POLB P06746 2/20 0.62
PSMD14 O00487 1/20 0.62
MMP2 P08253 1/20 0.62
BLM P54132 1/20 0.62
SMN1; SMN2 Q16637 1/20 0.62
SIRT1 Q96EB6 3/20 0.60
PIK3CG P48736 1/20 0.59
NPC1 O15118 2/20 0.58
MITF O75030 1/20 0.58
GPR174 Q9BXC1 1/20 0.58
L3MBTL1 Q9Y468 1/20 0.58
TDP1 Q9NUW8 2/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15127223 0.92 POLB (0.68) MAPTKDM1AKMT2AMEN1RAB9A
SCHEMBL684222 0.92 KDM1A (0.71) KDM1AKMT2AMEN1RAB9AKDM4E
SCHEMBL684527 0.90 KDM1A (0.81) MAPTKDM1AKMT2AMEN1RAB9A
SCHEMBL26974375 0.89 MAPT (0.72) MAPTKDM1AKMT2AMEN1RAB9A
SCHEMBL684894 0.88 KDM1A (0.66) MAPTKDM1AKMT2AMEN1RAB9A
SCHEMBL684659 0.86 KDM1A (0.70) MAPTKDM1AKMT2AMEN1RAB9A
SCHEMBL12746377 0.86 SIRT1 (0.72) MAPTKDM1AKMT2AMEN1RAB9A
SCHEMBL684769 0.86 KDM1A (0.66) MAPTKDM1AKMT2AMEN1RAB9A
SCHEMBL684899 0.85 PIK3CG (0.82) MAPTKDM1AKMT2AMEN1RAB9A
SCHEMBL685064 0.84 KDM1A (0.72) MAPTKDM1AKMT2AMEN1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8715745-B2 Fungicidal compositions including hydrazone derivatives and copper DOW AGROSCIENCES, LLC. (US) 2014-05-06 US disclosed
US-8715745-B2 Fungicidal compositions including hydrazone derivatives and copper DOW AGROSCIENCES, LLC. (US) 2014-05-06 US disclosed
US-20120010075-A1 SYNERGISTIC FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER DOW AGROSCIENCES LLC (US) 2012-01-12 US disclosed
US-20120009274-A1 FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER DOW AGROSCIENCES LLC (US) 2012-01-12 US disclosed
US-20120009274-A1 FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER DOW AGROSCIENCES LLC (US) 2012-01-12 US disclosed
US-20120010075-A1 SYNERGISTIC FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER DOW AGROSCIENCES LLC (US) 2012-01-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120010075-A1 SYNERGISTIC FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER SOD1, CYP51A1, SOD3 MAPT 1491/4885KDM1A 484/4885KMT2A 1362/4885
US-20120009274-A1 FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER SOD1, CYP51A1, CYP4Z1 MAPT 921/4885KDM1A 291/4885KMT2A 1224/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.