Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | ANPEP | P15144 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6388000 | 0.82 | CTSS (0.44) | RNPEPLMNATSHRCTSSCTSK | |
| SCHEMBL10296118 | 0.82 | LMNA (0.42) | RNPEPLMNAANPEPMAPK1GAA | |
| Hydrochloric Acid SCHEMBL11457412 | 0.82 | RNPEP (0.41) | RNPEPLMNATSHRCTSSCTSK | |
| SCHEMBL10296038 | 0.82 | LMNA (0.42) | RNPEPLMNATSHRCTSSCTSK | |
| SCHEMBL13865575 | 0.82 | DRD1 (0.42) | LMNATSHRCTSSCTSKANPEP | |
| SCHEMBL23753625 | 0.82 | CTSS (0.44) | RNPEPLMNATSHRCTSSCTSK | |
| SCHEMBL17928531 | 0.81 | TSHR (0.43) | RNPEPLMNATSHRCTSSCTSK | |
| SCHEMBL12597432 | 0.81 | RNPEP (0.42) | RNPEPLMNATSHRCTSSCTSK | |
| SCHEMBL76427 | 0.81 | RNPEP (0.52) | RNPEPLMNAMAPK1GAAALDH1A1 | |
| SCHEMBL12038890 | 0.81 | RNPEP (0.42) | RNPEPLMNATSHRCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3849981-B1 | PYRAZOLO[1,5-A]PYRIMIDINE-3-CARBOXAMIDE DERIVATIVES USEFUL IN THE TREATMENT OF PSORIASIS AND SYSTEMIC LUPUS ERYTHEMATOSUS | LILLY CO ELI (US) | 2023-02-01 | — | — | EP | disclosed |
| WO-2011157612-A2 | AMINO ACID DERIVATIVES; COMPOSITIONS CONTAINING THEM; USE AS AGENTS FOR TREATING HUMAN PERSPIRATION | L'OREAL (FR) | 2011-12-22 | — | — | WO | disclosed |
| US-20110150820-A1 | METHODS FOR COVALENTLY ATTACHING A POLYMER TO A METHIONINE RESIDUE IN PROTEINS AND PEPTIDES | INSIGHT BIOPHARMACEUTICALS LTD. (IL) | 2011-06-23 | — | — | US | disclosed |
| US-20110150837-A1 | Amphiphilic polymer functionalized by methionine | FLAMEL TECHNOLOGIES (FR) | 2011-06-23 | — | — | US | disclosed |
| US-20080145863-A1 | Affinity selected signature peptides for protein identification and quantification | PURDUE RESEARCH FOUNDATION (US) | 2008-06-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110150837-A1 | Amphiphilic polymer functionalized by methionine | MTR, LNPEP, METAP1 | RNPEP 334/4885LMNA 4005/4885TSHR 3037/4885 |
| US-20110150820-A1 | METHODS FOR COVALENTLY ATTACHING A POLYMER TO A METHIONINE RESIDUE IN PROTEINS AND PEPTIDES | LNPEP, MGMT, DNPEP | RNPEP 72/4885LMNA 4380/4885TSHR 1564/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.