Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPM1B | O75688 | 1/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | GFER | P55789 | 1/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | ACMSD | Q8TDX5 | 3/20 | 0.52 |
| ▸ | HNF4A | P41235 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23499274 | 0.92 | PPM1B (0.79) | PPM1BKDM4EKMT2AGFERRXFP1 | |
| SCHEMBL29908977 | 0.92 | PPM1B (0.79) | PPM1BKDM4EKMT2AGFERRXFP1 | |
| SCHEMBL710309 | 0.90 | PPM1B (0.75) | PPM1BKDM4EKMT2AGFERRXFP1 | |
| SCHEMBL29436316 | 0.90 | PPM1B (0.75) | PPM1BKDM4EKMT2AGFERRXFP1 | |
| SCHEMBL30456877 | 0.86 | PPM1B (0.71) | PPM1BKDM4EKMT2AGFERRXFP1 | |
| SCHEMBL2575452 | 0.86 | PPM1B (0.71) | PPM1BKDM4EKMT2AGFERRXFP1 | |
| SCHEMBL30314350 | 0.86 | PPM1B (0.70) | PPM1BKDM4EKMT2AGFERRXFP1 | |
| SCHEMBL17177763 | 0.86 | PPM1B (0.70) | PPM1BKDM4EKMT2AGFERRXFP1 | |
| SCHEMBL28033110 | 0.85 | PPM1B (0.54) | PPM1BKDM4EKMT2AGFERRXFP1 | |
| SCHEMBL30504245 | 0.85 | PPM1B (0.69) | PPM1BKDM4EKMT2AGFERRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1820795-A1 | NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 2007-08-22 | — | — | EP | disclosed |
| EP-1294378-A4 | THROMBOPOIETIN MIMETICS | SMITHKLINE BEECHAM CORP (US) | 2004-01-28 | — | — | EP | disclosed |
| EP-1294378-A2 | THROMBOPOIETIN MIMETICS | SMITHKLINE BEECHAM CORPORATION (US) | 2003-03-26 | — | — | EP | disclosed |
| WO-2001089457-A2 | THROMBOPOIETIN MIMETICS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-11-29 | — | — | WO | disclosed |