SCHEMBL6851180

SCHEMBL6851180

Cc1[nH]c2c(O)cc3c(c2c1C(=O)O)[C@H](CCl)CN3C(=O)OC(C)(C)C

nearest known ligand 0.36

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ADH1A P07327 1/20 0.36
KIT P10721 1/20 0.36
FLT1 P17948 1/20 0.36
FLT4 P35916 1/20 0.36
KDR P35968 1/20 0.36
ABL2 P42684 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6851179 0.88 ADH1A (0.35) ADH1AKITFLT1FLT4KDR
SCHEMBL6855095 0.82 ADH1A (0.37) ADH1AKITFLT1FLT4KDR
SCHEMBL8913783 0.82 ADH1A (0.38) ADH1AKITFLT1FLT4KDR
SCHEMBL8915100 0.82 ADH1A (0.38) ADH1AKITFLT1FLT4KDR
SCHEMBL7474530 0.81 ADH1A (0.34) ADH1AKITFLT1FLT4KDR
SCHEMBL6852340 0.81 ADH1A (0.44) ADH1AKITFLT1FLT4KDR
SCHEMBL8057581 0.77 ADH1A (0.39) ADH1AKITFLT1FLT4KDR
SCHEMBL29723161 0.76 ADH1A (0.38) ADH1AKITFLT1FLT4KDR
SCHEMBL28420655 0.76 ADH1A (0.38) ADH1AKITFLT1FLT4KDR
SCHEMBL29723308 0.76 ADH1A (0.38) ADH1AKITFLT1FLT4KDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6828417-B2 For measurement of analytes to be measured in samples derived from living bodies, such as body fluids (e.g. serum, blood, plasma, urine, etc.), lymphocyte, hemocyte, and various cells WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2004-12-07 US disclosed
EP-0799827-B1 ACRYLAMIDE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME KYORIN SEIYAKU KK (JP) 2004-05-12 EP disclosed
US-6300079-B1 REACTING BODY FLUID SAMPLES HAVING AN ANALYTE CONTAINING A POLYPEPTIDE BOUND TO AN AFFINITY SUBSTANCE, THE POLYPEPTIDE HAVING AT LEAST 3 ACID RESIDUES FROM A STRONG ACID, FORMING AND SEPARATING THE COMPLEX FORMED USING ANION EXCHANGE HAVING WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2001-10-09 US disclosed
US-5786486-A ANTIMICROBIAL, ANTITUMOR AGENTS KYORIN PHARMACEUTICAL CO., LTD. (JP) 1998-07-28 US disclosed
EP-0799827-A1 ACRYLAMIDE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME KYORIN PHARMACEUTICAL CO., LTD. (JP) 1997-10-08 EP disclosed