Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1A | P07327 | 2/20 | 0.44 |
| ▸ | KIT | P10721 | 2/20 | 0.44 |
| ▸ | FLT1 | P17948 | 2/20 | 0.44 |
| ▸ | KDR | P35968 | 2/20 | 0.44 |
| ▸ | ABL2 | P42684 | 2/20 | 0.44 |
| ▸ | FLT4 | P35916 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | EIF4A3 | P38919 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6998368 | 0.83 | SRD5A2 (0.41) | ADH1AKITFLT1KDRABL2 | |
| SCHEMBL6618596 | 0.81 | ADH1A (0.46) | ADH1AKITFLT1KDRABL2 | |
| SCHEMBL6851180 | 0.81 | ADH1A (0.36) | ADH1AKITFLT1KDRABL2 | |
| SCHEMBL7954292 | 0.81 | ADH1A (0.32) | ADH1AKITFLT1KDRABL2 | |
| SCHEMBL6855095 | 0.80 | ADH1A (0.37) | ADH1AKITFLT1KDRABL2 | |
| SCHEMBL1899623 | 0.79 | ADH1A (0.65) | ADH1AKITFLT1KDRABL2 | |
| SCHEMBL18089333 | 0.79 | ADH1A (0.65) | ADH1AKITFLT1KDRABL2 | |
| SCHEMBL29416531 | 0.79 | ADH1A (0.65) | ADH1AKITFLT1KDRABL2 | |
| SCHEMBL16781599 | 0.79 | ADH1A (0.65) | ADH1AKITFLT1KDRABL2 | |
| SCHEMBL1903631 | 0.79 | ADH1A (0.65) | ADH1AKITFLT1KDRABL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0799827-B1 | ACRYLAMIDE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | KYORIN SEIYAKU KK (JP) | 2004-05-12 | — | — | EP | disclosed |
| EP-0937726-B1 | INTERMEDIATES FOR THE PREPARATION OF DUOCARMYCIN SA AND DERIVATIVES THEREOF, AND PROCESS FOR THE PRODUCTION OF THE INTERMEDIATES | KYORIN SEIYAKU KK (JP) | 2003-03-12 | — | — | EP | disclosed |
| US-6066742-A | Intermediates for the preparation of duocarmycin SA and derivatives thereof, and process for the production of the intermediates | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2000-05-23 | — | — | US | disclosed |
| EP-0937726-A1 | INTERMEDIATES FOR THE PREPARATION OF DUOCARMYCIN SA AND DERIVATIVES THEREOF, AND PROCESS FOR THE PRODUCTION OF THE INTERMEDIATES | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1999-08-25 | — | — | EP | disclosed |
| US-5786486-A | ANTIMICROBIAL, ANTITUMOR AGENTS | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1998-07-28 | — | — | US | disclosed |
| EP-0799827-A1 | ACRYLAMIDE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1997-10-08 | — | — | EP | disclosed |