Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1A | P07327 | 1/20 | 0.35 |
| ▸ | KIT | P10721 | 1/20 | 0.35 |
| ▸ | FLT1 | P17948 | 1/20 | 0.35 |
| ▸ | FLT4 | P35916 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | ABL2 | P42684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7474530 | 0.91 | ADH1A (0.34) | ADH1AKITFLT1FLT4KDR | |
| SCHEMBL6851180 | 0.88 | ADH1A (0.36) | ADH1AKITFLT1FLT4KDR | |
| SCHEMBL7474754 | 0.84 | TACR1 (0.33) | ADH1AKITFLT1FLT4KDR | |
| SCHEMBL7464610 | 0.84 | — | — | |
| SCHEMBL7463578 | 0.80 | LEF1 (0.36) | ADH1AKITFLT1FLT4KDR | |
| SCHEMBL6855095 | 0.80 | ADH1A (0.37) | ADH1AKITFLT1FLT4KDR | |
| SCHEMBL7465921 | 0.79 | ALDH1A1 (0.37) | — | |
| SCHEMBL7465748 | 0.79 | ALDH1A1 (0.37) | — | |
| SCHEMBL6852340 | 0.79 | ADH1A (0.44) | ADH1AKITFLT1FLT4KDR | |
| SCHEMBL8831050 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0799827-B1 | ACRYLAMIDE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | KYORIN SEIYAKU KK (JP) | 2004-05-12 | — | — | EP | disclosed |
| EP-0656360-B1 | TRIFLUOROMETHYLPYRROLOINDOLE CARBOXYLIC ESTER DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | KYORIN SEIYAKU KK (JP) | 2002-11-20 | — | — | EP | disclosed |
| US-5786486-A | ANTIMICROBIAL, ANTITUMOR AGENTS | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1998-07-28 | — | — | US | disclosed |
| EP-0799827-A1 | ACRYLAMIDE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1997-10-08 | — | — | EP | disclosed |
| US-5629430-A | ANTICARCINOGENIC AGENTS | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0656360-A1 | TRIFLUOROMETHYLPYRROLOINDOLE CARBOXYLIC ESTER DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1995-06-07 | — | — | EP | disclosed |