Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 3/20 | 0.33 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GRM6 | O15303 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.30 |
| ▸ | PSAT1 | Q9Y617 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11530324 | 0.67 | POLB (0.41) | LMNATHRBTDP1 | |
| SCHEMBL6849579 | 0.62 | KDM4E (0.36) | GRM2GRM3LMNAGRM6SRR | |
| SCHEMBL28121326 | 0.61 | ALDH1A1 (0.41) | LMNATDP1 | |
| SCHEMBL14991617 | 0.61 | HNF4A (0.34) | GRM2GRM3LMNATHRBTDP1 | |
| SCHEMBL17480245 | 0.59 | ALDH1A1 (0.42) | LMNATDP1 | |
| SCHEMBL6570406 | 0.58 | CYP1A2 (0.41) | LMNATP53TDP1 | |
| Biphenyl SCHEMBL1326612 | 0.56 | ALDH1A1 (0.60) | LMNA | |
| Biphenyl SCHEMBL473288 | 0.56 | ALDH1A1 (0.60) | LMNATDP1 | |
| Biphenyl SCHEMBL4593266 | 0.56 | ALDH1A1 (0.60) | LMNATDP1 | |
| Biphenyl SCHEMBL335359 | 0.56 | ALDH1A1 (0.60) | LMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1294378-A4 | THROMBOPOIETIN MIMETICS | SMITHKLINE BEECHAM CORP (US) | 2004-01-28 | — | — | EP | disclosed |
| EP-1294378-A2 | THROMBOPOIETIN MIMETICS | SMITHKLINE BEECHAM CORPORATION (US) | 2003-03-26 | — | — | EP | disclosed |
| WO-2001089457-A2 | THROMBOPOIETIN MIMETICS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-11-29 | — | — | WO | disclosed |