SCHEMBL6851372

SCHEMBL6851372

CCOC(=O)C(CC)(CC#N)P(=O)(O)O

nearest known ligand 0.45

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
ALDH1A1 P00352 3/20 0.33
CYP4F2 P78329 2/20 0.33
CYP4A11 Q02928 2/20 0.33
TSHR P16473 1/20 0.33
MMP8 P22894 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.31
PKM P14618 2/20 0.31
KDM4E B2RXH2 1/20 0.31
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18759662 0.84 CYP4F2 (0.40) MEN1KMT2AALDH1A1CYP4F2CYP4A11
SCHEMBL16048 0.84 CYP4F2 (0.40) MEN1KMT2AALDH1A1CYP4F2CYP4A11
SCHEMBL413276 0.82 CYP4F2 (0.39) MEN1KMT2AALDH1A1CYP4F2CYP4A11
SCHEMBL19278938 0.82 CYP4F2 (0.39) MEN1KMT2AALDH1A1CYP4F2CYP4A11
SCHEMBL651926 0.77 FDPS (0.44) MEN1KMT2AALDH1A1CYP4F2CYP4A11
SCHEMBL9064918 0.75 MMP8 (0.50) MEN1KMT2AALDH1A1CYP4F2CYP4A11
SCHEMBL8171534 0.75 PIN1 (0.39) MEN1KMT2AALDH1A1CYP4F2CYP4A11
SCHEMBL2237636 0.75 FDPS (0.43) MEN1KMT2ACYP4F2CYP4A11PKM
SCHEMBL2392569 0.73 CYP4F2 (0.33) MEN1KMT2AALDH1A1CYP4F2CYP4A11
SCHEMBL22446015 0.73 MMP8 (0.38) MEN1KMT2AALDH1A1CYP4F2CYP4A11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040087633-A1 Methylidene oxazolidinone compound and preparation method thereof KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2004-05-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040087633-A1 Methylidene oxazolidinone compound and preparation method thereof OXA1L, TET1, TET2 MEN1 342/4885KMT2A 501/4885ALDH1A1 1232/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.