Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 14/20 | 0.43 |
| ▸ | THRA | P10827 | 11/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6852826 | 0.87 | POLB (0.45) | POLBGAAGFERTHRBTHRA | |
| SCHEMBL6852819 | 0.87 | POLB (0.45) | POLBGAAGFERTHRBTHRA | |
| SCHEMBL6855029 | 0.83 | GAA (0.45) | POLBGAAGFERTHRBTHRA | |
| SCHEMBL6658124 | 0.80 | THRB (0.45) | POLBGAAGFERTHRBTHRA | |
| SCHEMBL6852972 | 0.80 | THRB (0.60) | POLBGAAGFERTHRBTHRA | |
| SCHEMBL6658703 | 0.78 | THRB (0.44) | POLBGAAGFERTHRBTHRA | |
| SCHEMBL6657368 | 0.75 | THRA (0.56) | THRBTHRA | |
| SCHEMBL4961949 | 0.74 | POLB (0.43) | POLBGAAGFERTHRBTHRA | |
| SCHEMBL7568596 | 0.73 | GAA (0.50) | POLBGAAGFERTHRBTHRA | |
| SCHEMBL6853063 | 0.73 | THRA (0.35) | POLBGAAGFERTHRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6777442-B2 | Diphenyl derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2004-08-17 | — | — | US | disclosed |
| US-20030105078-A1 | Diphenyl derivatives | BAYER AKTIENGESSELLSCHAFT (DE) | 2003-06-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030105078-A1 | Diphenyl derivatives | DPP4, DPP3, DPM1 | POLB 1714/4885GAA 2118/4885GFER 3143/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.