Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 19/20 | 0.58 |
| ▸ | THRA | P10827 | 18/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6854588 | 0.87 | MMP1 (0.46) | THRBTHRAALDH1A1 | |
| SCHEMBL6854271 | 0.85 | PPARA (0.40) | THRBTHRAALDH1A1 | |
| SCHEMBL6856861 | 0.85 | THRB (0.51) | THRBTHRA | |
| SCHEMBL6856728 | 0.82 | PTGDR2 (0.38) | THRBTHRAALDH1A1 | |
| SCHEMBL6852992 | 0.82 | THRA (0.57) | THRBTHRAALDH1A1 | |
| SCHEMBL23003762 | 0.82 | THRB (0.66) | THRBTHRA | |
| SCHEMBL6854042 | 0.81 | THRA (0.40) | THRBTHRAALDH1A1 | |
| SCHEMBL7569701 | 0.76 | GAA (0.41) | ALDH1A1 | |
| SCHEMBL23003721 | 0.76 | THRB (0.57) | THRBTHRA | |
| SCHEMBL20601960 | 0.74 | THRB (0.67) | THRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6777442-B2 | Diphenyl derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2004-08-17 | — | — | US | disclosed |
| US-20030105078-A1 | Diphenyl derivatives | BAYER AKTIENGESSELLSCHAFT (DE) | 2003-06-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030105078-A1 | Diphenyl derivatives | DPP4, DPP3, DPM1 | THRB 4614/4885THRA 4665/4885ALDH1A1 922/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.