Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 10/20 | 0.40 |
| ▸ | THRA | P10827 | 6/20 | 0.40 |
| ▸ | THRB | P10828 | 6/20 | 0.40 |
| ▸ | PPARG | P37231 | 5/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.37 |
| ▸ | PPARD | Q03181 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6852990 | 0.85 | THRB (0.58) | THRATHRBALDH1A1 | |
| SCHEMBL6854588 | 0.82 | MMP1 (0.46) | THRATHRBPTGDR2ALDH1A1GAA | |
| SCHEMBL6854274 | 0.82 | PPARA (0.41) | PPARATHRATHRBPPARGPPARD | |
| SCHEMBL6854042 | 0.81 | THRA (0.40) | THRATHRBPTGDR2ALDH1A1GAA | |
| SCHEMBL6856728 | 0.80 | PTGDR2 (0.38) | THRATHRBPTGDR2ALDH1A1GAA | |
| SCHEMBL28786151 | 0.76 | THRB (0.68) | PPARATHRATHRBPPARG | |
| SCHEMBL7569701 | 0.75 | GAA (0.41) | ALDH1A1GAA | |
| SCHEMBL6849586 | 0.71 | OPRK1 (0.42) | PPARA | |
| SCHEMBL6856861 | 0.71 | THRB (0.51) | PPARATHRATHRBPPARGPPARD | |
| SCHEMBL4211357 | 0.68 | THRB (0.50) | THRATHRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6777442-B2 | Diphenyl derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2004-08-17 | — | — | US | disclosed |
| US-20030105078-A1 | Diphenyl derivatives | BAYER AKTIENGESSELLSCHAFT (DE) | 2003-06-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030105078-A1 | Diphenyl derivatives | DPP4, DPP3, DPM1 | PPARA 52/4885THRA 4665/4885THRB 4614/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.