Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 2/20 | 0.47 |
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.40 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.40 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8006413 | 0.81 | CARM1 (0.42) | HRH1HTR2ACARM1PRMT6PRMT8 | |
| SCHEMBL14276380 | 0.77 | TSHR (0.45) | HRH1HTR2AAOC3TSHRNR3C1 | |
| SCHEMBL24176562 | 0.77 | TSHR (0.45) | HRH1HTR2AAOC3TSHRNR3C1 | |
| SCHEMBL24176560 | 0.77 | TSHR (0.45) | HRH1HTR2AAOC3TSHRNR3C1 | |
| SCHEMBL1443955 | 0.75 | HRH1 (0.59) | HRH1HTR2ATAAR1AOC3 | |
| SCHEMBL608453 | 0.74 | TSHR (0.54) | HTR2ACARM1PRMT6PRMT8TAAR1 | |
| Hydrochloric Acid SCHEMBL27658035 | 0.72 | TSHR (0.52) | HTR2ACARM1PRMT6PRMT8MAOA | |
| SCHEMBL14008625 | 0.71 | ADRA2B (0.40) | HRH1HTR2AAOC3TSHRNR3C1 | |
| SCHEMBL16461564 | 0.70 | CARM1 (0.43) | HRH1HTR2ACARM1PRMT6PRMT8 | |
| SCHEMBL25047097 | 0.70 | BCHE (0.41) | HRH1HTR2ATSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0959975-B1 | NOVEL AFFINITY LIGANDS AND THEIR USE | NOVO NORDISK AS (DK) | 2004-12-29 | — | — | EP | disclosed |
| US-6117996-A | COMPLEXING; SEPARATION; PURIFICATION OF PROTEINS | NOVO NORDISK A/S (DK) | 2000-09-12 | — | — | US | disclosed |