Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 1/20 | 0.42 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.42 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6853025 | 0.81 | HRH1 (0.47) | CARM1PRMT6PRMT8HTR2AHRH1 | |
| SCHEMBL608453 | 0.76 | TSHR (0.54) | CARM1PRMT6PRMT8HTR2ASLC6A2 | |
| Hydrochloric Acid SCHEMBL27658035 | 0.74 | TSHR (0.52) | CARM1PRMT6PRMT8HTR2ASLC6A2 | |
| SCHEMBL16390836 | 0.74 | CSNK1E (0.48) | SIGMAR1AOC3TSHRKCNH2ALDH1A1 | |
| SCHEMBL7991105 | 0.73 | MAOA (0.46) | CARM1PRMT6PRMT8HTR2AHRH1 | |
| SCHEMBL16461564 | 0.72 | CARM1 (0.43) | CARM1PRMT6PRMT8HTR2AHRH1 | |
| SCHEMBL24176560 | 0.72 | TSHR (0.45) | HTR2AHRH1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL14276380 | 0.72 | TSHR (0.45) | HTR2AHRH1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL24176562 | 0.72 | TSHR (0.45) | HTR2AHRH1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3874218 | 0.71 | SIGMAR1 (0.53) | CARM1PRMT6PRMT8HTR2AHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6117996-A | COMPLEXING; SEPARATION; PURIFICATION OF PROTEINS | NOVO NORDISK A/S (DK) | 2000-09-12 | — | — | US | disclosed |