Sugi Predict

Sugi Predict / Compounds / SCHEMBL6853136

SCHEMBL6853136

SCHEMBL6853136

CCO[Si](C)(OCC)c1ccc(N(c2ccc(N(c3cccc(C)c3)c3cccc(C)c3)cc2)c2cccc(C)c2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 4/20 0.38
▸ HTT P42858 3/20 0.38
▸ MEN1 O00255 3/20 0.38
▸ TSHR P16473 1/20 0.38
▸ POLQ O75417 5/20 0.36
▸ NPC1 O15118 2/20 0.35
▸ ALDH1A1 P00352 2/20 0.35
▸ RAB9A P51151 2/20 0.35
▸ PAX8 Q06710 2/20 0.35
▸ TP53 P04637 2/20 0.35
▸ GPX4 P36969 1/20 0.35
▸ JAK2 O60674 1/20 0.33
▸ MAPT P10636 4/20 0.33
▸ NR1I2 O75469 1/20 0.33
▸ LMNA P02545 1/20 0.33
▸ CYP1A2 P05177 1/20 0.33
▸ CYP3A4 P08684 1/20 0.33
▸ CYP2C9 P11712 1/20 0.33
▸ MAPK1 P28482 1/20 0.33
▸ CYP2C19 P33261 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6858713 0.96 HTT (0.36) KMT2AHTTMEN1TSHRPOLQ
SCHEMBL6851969 0.91 ADRA2A (0.32) KMT2AHTTMEN1TSHRTP53
SCHEMBL6744731 0.88 KMT2A (0.38) KMT2AHTTMEN1TSHRPOLQ
SCHEMBL6852490 0.88 ALDH1A1 (0.36) KMT2AMEN1TSHRALDH1A1MAPT
SCHEMBL6854722 0.87 ALDH1A1 (0.33) KMT2AHTTMEN1TSHRALDH1A1
SCHEMBL6748724 0.86 POLQ (0.40) KMT2AHTTMEN1TSHRPOLQ
SCHEMBL6851689 0.86 — —
SCHEMBL6852172 0.84 CYP2C19 (0.39) KMT2AMEN1TSHRNPC1ALDH1A1
SCHEMBL6846645 0.84 CYP2C19 (0.39) KMT2AMEN1TSHRNPC1ALDH1A1
SCHEMBL6848590 0.84 CYP2C19 (0.39) KMT2AMEN1TSHRNPC1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6696588-B2 OXIDATION POTENTIAL OF .3-1.5 V ON THE BASIS OF A STANDARD HYDROGEN ELECTRODE, ALKOXY AND AROMATIC AMINE DERIVATIVES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-02-24 — — US disclosed
EP-0861845-B1 Silicon-containing compound and organic electroluminescence device using the same SUMITOMO CHEMICAL CO (JP) 2003-05-28 — — EP disclosed
US-20020115877-A1 Silicon-containing compound and organic electroluminescence device using the same SUMITOMO CHEMICAL COMPANY, LIMITED 2002-08-22 — — US disclosed
US-6369258-B1 SILICON COMPOUND WITH OXIDATION POTENTIAL ON HYDROGEN ELECTRODE POTENTIAL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-04-09 — — US disclosed
EP-0861845-A2 Silicon-containing compound and organic electroluminescence device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-09-02 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020115877-A1 Silicon-containing compound and organic electroluminescence device using the same EPCAM, PIEZO1, OR10J3 KMT2A 591/4885HTT 3465/4885MEN1 3062/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.