Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 4/20 | 0.56 |
| ▸ | ACE | P12821 | 2/20 | 0.40 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGAV | P06756 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6861799 | 0.84 | ADRA1A (0.58) | PLA2G2AALDH1A1LMNA | |
| SCHEMBL652671 | 0.84 | USP2 (0.50) | ECE1ALDH1A1LMNAMAPTPTGS2 | |
| SCHEMBL5964414 | 0.82 | ECE1 (0.60) | ECE1ACEMMEPLA2G2AITGB3 | |
| Water SCHEMBL27800796 | 0.80 | ECE1 (0.58) | ECE1ACEMMEPLA2G2AITGB3 | |
| Water SCHEMBL28289443 | 0.80 | ECE1 (0.58) | ECE1ACEMMEPLA2G2AITGB3 | |
| SCHEMBL5519706 | 0.79 | ALDH1A2 (0.50) | ALDH1A1 | |
| SCHEMBL25328393 | 0.79 | TSHR (0.46) | ECE1ALDH1A1LMNAMAPT | |
| SCHEMBL28185842 | 0.79 | ECE1 (0.53) | ECE1ACEMMEPLA2G2AITGB3 | |
| SCHEMBL7290638 | 0.78 | ECE1 (0.58) | ECE1ACEMMEPLA2G2AITGB3 | |
| SCHEMBL7290633 | 0.78 | ECE1 (0.58) | ECE1ACEMMEPLA2G2AITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946525-B1 | METHOD FOR PRODUCING METAL COMPLEX CARBOXYLIC ACID AMIDES | SCHERING AG (DE) | 2004-04-07 | — | — | EP | disclosed |
| EP-0946526-B1 | MACROCYCLIC METAL COMPLEX CARBOXYLIC ACIDS, USE AND METHOD FOR THE PRODUCTION THEREOF | SCHERING AG (DE) | 2003-10-29 | — | — | EP | disclosed |
| US-6045776-A | Process for the production of metal-complex carboxylic acid amides | SCHERING AKTIENGESELLSCHAFT (DE) | 2000-04-04 | — | — | US | disclosed |
| US-5919433-A | NUCLEAR MAGNETIC RESONANCE | SCHERING AKTIENGESELLSCHAFT (DE) | 1999-07-06 | — | — | US | disclosed |