Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 1/20 | 0.58 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.57 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 10/20 | 0.45 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.44 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3675888 | 0.88 | ALDH1A1 (0.54) | MAPK1LMNAALDH1A2ALDH1A1ALDH2 | |
| SCHEMBL5519706 | 0.86 | ALDH1A2 (0.50) | MAPK1TSHRALDH1A2ALDH1A1ALDH2 | |
| SCHEMBL27052896 | 0.85 | ADRA1A (0.62) | ADRA1APRMT1PLA2G2AMAPK1EPHX2 | |
| SCHEMBL9829389 | 0.85 | ADRA1A (0.62) | ADRA1APRMT1PLA2G2AMAPK1EPHX2 | |
| SCHEMBL6853455 | 0.84 | ECE1 (0.56) | PLA2G2ALMNAALDH1A1 | |
| SCHEMBL9830431 | 0.82 | ADRA1A (0.59) | ADRA1APRMT1PLA2G2AMAPK1EPHX2 | |
| SCHEMBL8390709 | 0.81 | ADRA1A (0.58) | ADRA1APRMT1PLA2G2AMAPK1EPHX2 | |
| SCHEMBL31188655 | 0.81 | EPHX1 (0.57) | — | |
| SCHEMBL18025977 | 0.80 | ADRA1A (0.56) | ADRA1APRMT1PLA2G2AMAPK1EPHX2 | |
| SCHEMBL16401723 | 0.80 | PRMT1 (0.55) | ADRA1APRMT1PLA2G2AMAPK1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946525-B1 | METHOD FOR PRODUCING METAL COMPLEX CARBOXYLIC ACID AMIDES | SCHERING AG (DE) | 2004-04-07 | — | — | EP | disclosed |
| EP-0946526-B1 | MACROCYCLIC METAL COMPLEX CARBOXYLIC ACIDS, USE AND METHOD FOR THE PRODUCTION THEREOF | SCHERING AG (DE) | 2003-10-29 | — | — | EP | disclosed |
| US-6045776-A | Process for the production of metal-complex carboxylic acid amides | SCHERING AKTIENGESELLSCHAFT (DE) | 2000-04-04 | — | — | US | disclosed |
| EP-0946526-A1 | MACROCYCLIC METAL COMPLEX CARBOXYLIC ACIDS, USE AND METHOD FOR THE PRODUCTION THEREOF | SCHERING AKTIENGESELLSCHAFT (DE) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998024774-A1 | MACROCYCLIC METAL COMPLEX CARBOXYLIC ACIDS, USE AND METHOD FOR THE PRODUCTION THEREOF | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-06-11 | — | — | WO | disclosed |