SCHEMBL6853490

SCHEMBL6853490

C[Si](C)(c1ccc(N)c(O)c1)c1ccc(N)c(O)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 4/20 0.50
HSD17B10 Q99714 3/20 0.50
CYP3A4 P08684 1/20 0.50
GAA P10253 6/20 0.45
MAPT P10636 4/20 0.45
MEN1 O00255 3/20 0.45
KMT2A Q03164 3/20 0.45
KDM4E B2RXH2 3/20 0.45
POLB P06746 1/20 0.45
RAB9A P51151 1/20 0.45
ESR1 P03372 3/20 0.40
ESR2 Q92731 3/20 0.40
TSHR P16473 2/20 0.37
ALDH1A1 P00352 6/20 0.37
HPGD P15428 2/20 0.35
RECQL P46063 2/20 0.33
ALOX12 P18054 2/20 0.33
PKM P14618 1/20 0.33
HTT P42858 1/20 0.33
HIF1A Q16665 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6852410 0.82 ALDH1A1 (0.52) ALOX15HSD17B10GAAMAPTMEN1
SCHEMBL11534628 0.78 CYP3A4 (0.46) ALOX15HSD17B10CYP3A4GAAMAPT
SCHEMBL6853462 0.78 GAA (0.42) ALOX15HSD17B10CYP3A4GAAMAPT
SCHEMBL3929512 0.73 CYP3A4 (0.50) ALOX15HSD17B10CYP3A4MAPTKDM4E
SCHEMBL29356215 0.69
SCHEMBL4866842 0.69 ALOX15 (0.65) ALOX15HSD17B10CYP3A4GAAMAPT
SCHEMBL33821 0.69
SCHEMBL13086248 0.68 ALDH1A1 (0.52) ALOX15HSD17B10CYP3A4GAAMAPT
SCHEMBL23924225 0.67 CYP3A4 (1.00) ALOX15HSD17B10CYP3A4GAAMAPT
SCHEMBL593274 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9410055-B2 Polybenzoxazole resin and precursor thereof MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2016-08-09 US disclosed
EP-2695906-A1 POLYBENZOXAZOLE RESIN AND PRECURSOR THEREOF Mitsubishi Gas Chemical Company, Inc. (JP) 2014-02-12 EP disclosed
US-20130324662-A1 POLYBENZOXAZOLE RESIN AND PRECURSOR THEREOF MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2013-12-05 US disclosed
US-6780561-B2 FOR FORMING PROTECTIVE FILM OR AN INSULATING FILM FOR A SEMICONDUCTOR ELEMENT OR A CIRCUIT BOARD SUCH AS A PRINTED BOARD KANSAI PAINT CO., LTD. (JP) 2004-08-24 US disclosed
US-20030143480-A1 For forming protective film or an insulating film for a semiconductor element or a circuit board such as a printed board KANSAI PAINT CO., LTD. (JP) 2003-07-31 US disclosed