Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 6/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6852410 | 0.78 | ALDH1A1 (0.52) | TDP1ALOX15SMN1; SMN2THRBMEN1 | |
| SCHEMBL6853490 | 0.78 | ALOX15 (0.50) | CYP3A4TDP1ALOX15SMN1; SMN2THRB | |
| SCHEMBL3929512 | 0.78 | CYP3A4 (0.50) | CYP3A4TDP1ALOX15SMN1; SMN2TP53 | |
| SCHEMBL4527953 | 0.74 | MEN1 (0.43) | CYP3A4TDP1ALOX15SMN1; SMN2TP53 | |
| SCHEMBL28755799 | 0.73 | CYP3A4 (0.41) | CYP3A4TDP1ALOX15SMN1; SMN2TP53 | |
| SCHEMBL3923695 | 0.69 | MEN1 (0.50) | CYP3A4TDP1ALOX15SMN1; SMN2TP53 | |
| SCHEMBL65963 | 0.69 | MEN1 (0.50) | CYP3A4TDP1ALOX15SMN1; SMN2TP53 | |
| SCHEMBL6422988 | 0.67 | CYP3A4 (0.52) | CYP3A4TDP1ALOX15TP53MEN1 | |
| SCHEMBL29437105 | 0.67 | CYP3A4 (0.52) | CYP3A4TDP1ALOX15TP53MEN1 | |
| SCHEMBL21183074 | 0.65 | ACHE (0.32) | CYP3A4TDP1ALOX15SMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4045414-A | New di-substituted meta-terphenyl compounds and resulting polymers | INSTITUT FRANCAIS DU PETROLE (FR) | 1977-08-30 | — | — | US | claimed |
| US-4147728-A | Disubstituted meta-terphenyl compounds and resulting polymers | INSTITUT FRANCAIS DU PETROLE (FR) | 1979-04-03 | — | — | US | disclosed |
| US-4064176-A | Di-substituted meta-terphenyl compounds and resulting polymers | INSTITUT FRANCAIS DU PETROLE (FR) | 1977-12-20 | — | — | US | disclosed |
| US-4045414-A | New di-substituted meta-terphenyl compounds and resulting polymers | INSTITUT FRANCAIS DU PETROLE (FR) | 1977-08-30 | — | — | US | disclosed |