Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 7/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL81884 | 0.81 | APLNR (0.56) | HTR2ATAAR1HTR2CCYP19A1 | |
| SCHEMBL6487286 | 0.79 | ADRA1A (0.41) | HTR2ATAAR1HTR2C | |
| SCHEMBL24119648 | 0.79 | HTR2A (0.61) | HTR2ATAAR1HTR2C | |
| SCHEMBL7265969 | 0.78 | ALDH1A1 (0.51) | HTR2ATAAR1HTR2C | |
| SCHEMBL79353 | 0.77 | TAAR1 (0.60) | TAAR1 | |
| SCHEMBL30118964 | 0.77 | TAAR1 (0.60) | TAAR1 | |
| SCHEMBL5309312 | 0.77 | HTR2A (0.70) | HTR2ATAAR1HTR2C | |
| SCHEMBL24783648 | 0.77 | TRAP1 (0.56) | HTR2ATAAR1 | |
| SCHEMBL24783635 | 0.77 | TRAP1 (0.56) | HTR2ATAAR1 | |
| SCHEMBL30859405 | 0.77 | TRAP1 (0.56) | HTR2ATAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1107971-B1 | PORPHYRIN DERIVATIVES, THEIR USE IN PHOTODYNAMIC THERAPY AND MEDICAL DEVICES CONTAINING THEM | DESTINY PHARMA LTD (GB) | 2004-11-24 | — | — | EP | disclosed |
| US-6630128-B1 | Insoluble support | DESTINY PHARMA LIMITED (GB) | 2003-10-07 | — | — | US | disclosed |